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SmartCage

Features

• Noninvasive multi-biosensors

• One system – multiple tests

• Up to 16 units of SmartCage run simultaneously by one PC

• Window based software

• Provide training and protocols

Applications

• Higher throughput behavioral phenotyping and in vivo drug screening
• Neurobehavioral toxicity screen
• Pharmacokinetics prediction using behavioral readouts

BEHAVIORAL TESTS PERFORMED BY ONE SmartCageTM

1. Locomotion: active time, travel distance, velocity and rearing (stand up). Position, and moving paths
2. Noninvasive total sleep/wake monitoring
3. Light/dark place preference and anxiety test
4. Social interaction (and social memory test)
5. Rotarod test in homecage
6. Foot drop/fault (with an option of footshock)
7. Feeding behavior (using a food gate)
8. Drinking behavior and conflict drinking
9. Step-through passive/active avoidance test
10. Tone/contextual conditioned fear test
11. Automated sleep deprivation
12. Drug (e.g., nicotine) aerosol delivery and self administration