With our patented compression technology, The Compresstome® overcomes these issues and can produce slices that have

  • More Live cells: Compression stabilizes the tissue, producing much more living cells on live tissues.
  • Smooth sections: tissue stabilization + Auto-Zero-Z® = No artifacts

Muscle tissues have the following characteristics that makes it difficult for traditional Vibratomes to section

  • Variability in tissue texture: Different types of muscle tissue, such as skeletal, cardiac, and smooth muscle, can have different textures and densities. This variability can make it challenging to produce uniform sections with a vibratome, and dense regions may cause the blade to skip or produce uneven section thickness.
  • Presence of delicate structures: Muscle tissue contains several delicate structures, such as blood vessels, nerves, and muscle fibers, that can be easily damaged during sectioning. The vibratome blade may tear or crumple these structures, leading to unusable or distorted sections.

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Real lab examples


Oliver SR, Wright VP, Parinandi N, Clanton TL. Thermal tolerance of contractile function in oxidative skeletal muscle: no protection by antioxidants and reduced tolerance with eicosanoid enzyme inhibition. Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1695-705. PMID: 18768765; PMCID: PMC2584865. Download PDF

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