Investigating lung development and regeneration using precision-cut lung slice (PCLS) models
Dr. Dean leads a research group at Imperial College London’s National Heart and Lung Institute, specializing in lung…
Organ: Lung
Advances in In Vitro Modeling of Lung Diseases: Focus on Precision-Cut Lung Slices (PCLS) Model
Dr. Hanan Osman-Ponchet is the accomplished Founder and CEO of PKDERM, a leading French biotech company specializing…
Precision cut lung slices (PCLS): A novel ex vivo model to study lung disease
Professor Koziol-White received her graduate degree from University of Wisconsin-Madison in Cellular and Molecular…
Slicing up the tumor: Lessons from attempted lung tumor slice cultures
Dr. Tsilingiri was born and raised in Athens, Greece. She studied Biochemistry and Biotechnology in Thessaly and then…
Immunology and Infection: The Compresstome® for Precision-Cut Lung Slices
The Compresstome® has been widely used by researchers worldwide for making precision-cut lung slices (PCLS). The Compresstome® uses agarose embedding prior to slicing to allow for the preservation of open alveoli and better tissue compliance. The video above shows Compresstome® sectioning PCLS for immunostaining to visualize the localization of various immune cell types in the lung. This protocol can be extended […]
Spatiotemporal Coordination of Stem Cell Behavior Following Alveolar Injury
In his PhD in Molecular Biology, working with Ben Hankamer at the Institute for Molecular Bioscience, University of…
Precision cut lung slices (PCLS) for probing mechanisms of pulmonary fibrosis
Claudia Loebel, M.D./Ph.D. is an Assistant Professor of Materials Science & Engineering and a Biological Sciences Scholar at the…
Using the Compresstome® in Immunotherapy Research
Dr Astero Klampatsa (PhD) is a Team Leader in Cancer Immunotherapy at the Institute of Cancer Research, London,…
