Adipose

Studying adipose tissue is crucial in research due to its central role in metabolism, energy storage, and its implications for obesity-related health issues. Obtaining healthy and high-quality tissue slices is paramount for accurate investigations involving adipose tissue. Quality samples ensure that researchers can examine cellular structures, gene expression, and molecular pathways accurately. This precision is essential for advancing our understanding of obesity, diabetes, and metabolic disorders, ultimately contributing to the development of effective treatments and interventions to improve public health.

Recommended Models

VF-510-0Z

Compresstome vibrating microtome

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RF-1000

Rotary microtome

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Real lab examples

References

Cautivo KM, Matatia PR, Lizama CO, Mroz NM, Dahlgren MW, Yu X, Sbierski-Kind J, Taruselli MT, Brooks JF, Wade-Vallance A, Caryotakis SE, Chang AA, Liang HE, Zikherman J, Locksley RM, Molofsky AB. Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation. Immunity. 2022 Feb 8;55(2):254-271.e7. PMID: 35139352; PMCID: PMC8852844. Download PDF

Morgan MM, Arendt LM, Alarid ET, Beebe DJ, Johnson BP. Mammary adipose stromal cells derived from obese women reduce sensitivity to the aromatase inhibitor anastrazole in an organotypic breast model. FASEB J. 2019 Jul;33(7):8623-8633. Epub 2019 Apr 19. PMID: 31002529; PMCID: PMC6593876. Download PDF