Eye

Conducting research involving eyes, like the mouse retina and cow eyes, is essential for gaining insights into vision, eye diseases, and ocular health. Obtaining healthy and precise tissue slices from eyes is critical for accurate investigations. High-quality samples ensure the examination of ocular structures, cellular compositions, and disease-related changes with precision. This precision is vital for advancing our understanding of vision disorders, eye treatments, and improving overall eye health, benefiting countless individuals affected by visual impairments and eye-related conditions.

Recommended Models

VF-510-0Z

Compresstome vibrating microtome

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RF-1000

Rotary microtome

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References

Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, ChandrasekaranP, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH. In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease. Nat Commun. 2021 Jul 13;12(1):4291. PMID: 34257302; PMCID: PMC8277817. Download PDF

Lewis TR, Shores CR, Cady MA, Hao Y, Arshavsky VY, Burns ME. The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice. Sci Rep. 2020 May 5;10(1):7538. PMID: 32371886; PMCID: PMC7200662. Download PDF

Rochon PL, Theriault C, Rangel Olguin AG, Krishnaswamy A. The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges. Elife. 2021 Sep 21;10:e70870. PMID: 34545809; PMCID: PMC8514235. Download PDF

Full references list

Protocol

617-682-0586

Organ system

Animals

Experiments

Eye

Recommended Models

VF-510-0Z

RF-1000

Real lab examples

References

Full references list

Protocol

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