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Material & Bio-engineering (Polymers)

Polymer, paint, and hard materials research is a branch of materials science that deals with the design, synthesis, and characterization of materials, such as polymers, coatings, and composites. This field of research is essential for developing new materials with improved mechanical, chemical, and physical properties that can be used in various applications, such as construction, aerospace, and automotive industries. Thin sample sections are required for in-depth analysis such as stress and strain of materials.

Advantages of the Compresstome®

Reduced structural damage: Tissue stabilization preserves structural integrity and details.
Smooth sections: tissue stabilization = No artifacts
Easy to maintain: Auto-Zero-Z means Zero-Z with no calibration needed.
Easy to learn: Many labs get great smooth slices on first or second try with the Compresstome.

Problems with traditional vibrating microtomes

Structural damage: Tissue tearing, folding, and shredding would compromise structural integrity.
Slice thickness variability: Inconsistent thickness can affect the repeatability of experiments.
Maintenance and calibration: Need time consuming maintenance requiring specialized knowledge or could lead to degrading performance.
Steep learning curve: Requires A LOT of practice to perfect, particularly for users who are new to IHC and tissue preparation.

Softer materials (biogel, scaffolding, tissue matrix, etc.):

Softer materials such as biogel, tissue matrix, organoids, can be sectioned easily with the Compresstome. Applications such as

Matrix & scaffolding sectioning for tissue bioengineering

See why the Compresstome is better.

Harder Tissues (hard plastic, bone etc.):

Hard materials can be sectioned easily with the Precisionary microtomes. Applications such as

Polymer sectioning for mechanical and materials science engineering
Paint defect analysis (injection molding with primers and paints) in the automotive industry
Hard materials including bone for biology and histopathology research

Precisionary Microtomes

Durability: Durable build with an industry leading 3 year warranty
Full Product line: available in automatic, semi-automatic, and manual (links for all) models
Easy to own: Solid supply chain and repair channels to ensure availability for your purchase and your maintenance.
Turnkey solution: All you need to get started comes with your microtome, so you can hit the ground running.

Recommended Models

RF-1000

Rotary microtome

Learn more

Not sure which model is right for your needs?

Real lab examples

Characterization of Biomechanical and Biotransport Properties of Meniscus: Investigating Their Relationships with Tissue Structure and Composition

Dr. Travascio described the key functions, structures and composition of the meniscus in the knee and explained experimental methods for characterizing tissue transport and mechanical properties for the meniscus.

References

Wang WY, Kent RN 3rd, Huang SA, Jarman EH, Shikanov EH, Davidson CD, Hiraki HL, Lin D, Wall MA, Matera DL, Shin JW, Polacheck WJ, Shikanov A, Baker BM. Direct comparison of angiogenesis in natural and synthetic biomaterials reveals that matrix porosity regulates endothelial cell invasion speed and sprout diameter. Acta Biomater. 2021 Nov;135:260-273. Epub 2021 Aug 29. PMID: 34469789; PMCID: PMC8595798. Download PDF

Zhou Y, Pereira G, Tang Y, James M, Zhang M. 3D Porous Scaffold-Based High-Throughput Platform for Cancer Drug Screening. Pharmaceutics. 2023 Jun 9;15(6):1691. PMID: 37376138; PMCID: PMC10304563. Download PDF

Full references list

Protocol

617-682-0586

Organ system

Animals

Experiments