Pigs have become a popular animal model in medical research due to their anatomical and physiological similarities to humans. They have been used to study a range of human diseases, including diabetes, cardiovascular diseases, and digestive disorders. Pigs are also used to test new surgical techniques and medical devices before clinical trials in humans.
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Cook DP, Rector MV, Bouzek DC, Michalski AS, Gansemer ND, Reznikov LR, Li X, Stroik MR, Ostedgaard LS, Abou Alaiwa MH, Thompson MA, Prakash YS, Krishnan R, Meyerholz DK, Seow CY, Stoltz DA. Cystic Fibrosis Transmembrane Conductance Regulator in Sarcoplasmic Reticulum of Airway Smooth Muscle. Implications for Airway Contractility. Am J Respir Crit Care Med. 2016 Feb 15;193(4):417-26. PMID: 26488271; PMCID: PMC4803085. Download PDF
McCarthy CM, Allardyce JM, Hickey SE, Walsh MT, McGourty KD, Mulvihill JJE. Comparison of macroscale and microscale mechanical properties of fresh and fixed-frozen porcine colonic tissue. J Mech Behav Biomed Mater. 2023 Feb;138:105599. Epub 2022 Nov 26. PMID: 36462287. Download PDF
Sponchiado M, Liao YS, Atanasova KR, Collins EN, Schurmann V, Bravo L, Reznikov LR. Overexpression of Substance P in pig airways increases MUC5AC through an NF-kβ pathway. Physiol Rep. 2021 Feb;9(3):e14749. PMID: 33580593; PMCID: PMC7881348. Download PDF
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