Upcoming Webinar | Dec. 17 | Serial Compresstome Vibratome Sectioning for Brain Mapping

APPLICATIONS | ORGANS

Tissue Sectioning Solutions for Kidney Studies

Create healthy, viable kidney tissue slices for PCKS and thin, consistent sections for immunological studies using Precisionary Instruments’ vibratome, rotary microtome, and cryostat.

High-Quality Kidney Tissue Slices for PCKS and Immunological Analysis

Kidney tissue sectioning is essential for creating precision-cut kidney slices (PCKS) for studying nephrology, toxicology, and disease models, as well as preparing thin sections for immunological analysis. 

Precisionary Instruments’ Compresstome VF-510-0Z vibratome enables researchers to produce healthy, viable PCKS from mouse and human kidney tissues, preserving the physiological structure for accurate nephrological studies. For more detailed analysis, the RF-1000 rotary microtome and CF-6100 cryostat allow for thin, consistent kidney sections ideal for immunohistochemistry, staining, and imaging. These tools ensure reproducible, high-quality results for both preclinical and clinical research in kidney studies.

Compresstome® VF-510-0Z

Precision Vibrating Microtome for Precision-Cut Kidney Slices (PCKS)

The Compresstome® VF-510-0Z vibratome is designed to create precision-cut kidney slices (PCKS) from mouse and human kidney tissue, preserving cellular integrity for nephrology and toxicology studies. This fully automated system produces thin, viable sections, ensuring accurate results for drug screening, disease models, and organ function studies.

Experimental applications include:

With a 5-year warranty, the VF-510-0Z delivers precision and reliability in producing healthy kidney tissue slices for research and clinical applications.

Rotary Microtome RF-1000

Fully Automated Microtome for Thin Kidney Tissue Sections

The RF-1000 rotary microtome is engineered to cut thin, uniform sections of kidney tissue, making it ideal for immunohistochemistry, histopathology, and advanced imaging studies. Its fully automated features provide researchers with reliable and consistent thin sectioning for detailed kidney analysis.

Experimental applications include:

With a 3-year warranty, the RF-1000 provides precision and stability for repetitive kidney tissue sectioning.

Cryostat CF-6100

Cryostat for Frozen Sectioning of Kidney Tissue

The CF-6100 cryostat offers precise frozen sectioning of kidney tissue embedded in OCT, ensuring the structural integrity of kidney samples during sectioning. This cryostat is ideal for preparing thin kidney sections for immunohistochemistry and other advanced research techniques.

Experimental applications include:

Acting as a laboratory workhorse, the CF-6100 ensures reliable frozen sectioning for kidney research over time.

TEC-200 Tissue Embedding Center

Efficient Tissue Processing for Kidney Studies

The TEC-200 Tissue Embedding Center is designed for seamless embedding. It offers automation for precise and consistent results. Ideal for kidney studies, its ergonomic design ensures operator comfort. Experience stability and precision cutting, and elevate your tissue processing with the TEC-200 from Precisionary Instruments.

References

Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, Chandrasekaran P, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH. In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease. Nat Commun. 2021 Jul 13;12(1):4291. PMID: 34257302; PMCID: PMC8277817.

Charrin E, Dabaghie D, Sen I, Unnersjö-Jess D, Möller-Hackbarth K, Burmakin M, Mencke R, Zambrano S, Patrakka J, Olauson H. Soluble Klotho protects against glomerular injury through regulation of ER stress response. Commun Biol. 2023 Feb 22;6(1):208. PMID: 36813870; PMCID: PMC9947099.

Ferreira P, Vaja R, Lopes-Pires M, Crescente M, Yu H, Nüsing R, Liu B, Zhou Y, Yaqoob M, Zhang A, Rickman M, Longhurst H, White WE, Knowles RB, Chan MV, Warner TD, Want E, Kirkby NS, Mitchell JA. Renal Function Underpins the Cyclooxygenase-2: Asymmetric Dimethylarginine Axis in Mouse and Man. Kidney Int Rep. 2023 Mar 23;8(6):1231-1238. PMID: 37284684; PMCID: PMC10239776.

Request a

Quote

Bring greater precision and consistency to your kidney tissue slices. Fill out the form to request a quote from Precisionary Instruments. We’ll respond within one business day.