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APPLICATIONS | animals

Tissue Sectioning Solutions for Rat Tissue Slicing

Create healthy, viable rat brain tissue slices for neurological and biomedical research using Precisionary Instruments’ advanced sectioning tools.

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Get High-Quality Rat Tissue Slices

Rats are a fundamental animal model in neurological and biomedical research due to their anatomical and physiological similarities to humans. The ability to produce high-quality, consistent brain tissue slices is essential for studying neurological disorders, brain function, and cognitive processes. Rat brains are used in a wide range of research areas, including neural circuit analysis, behavior studies, and disease modeling, providing crucial insights into human brain function and pathology.

In addition to brain tissue, other rat organs, such as the liver, heart, and kidneys, are commonly sectioned to study disease mechanisms, drug responses, and organ functions. High-quality tissue sections from rats are vital for understanding disease progression, treatment outcomes, and genetic factors in biomedical research.

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Compresstome® VF-510-0Z

Precision Vibrating Microtome for Rat Tissue Slices

The Compresstome® VF-510-0Z is specifically designed to produce precise, healthy rat brain slices, maintaining the structural integrity of the brain tissue. This vibratome is ideal for neurological research, behavioral studies, and disease models where consistent brain tissue slices are required. It also supports sectioning of other organs, such as the liver and kidneys.

Experimental Applications Include:

  • Precision-cut rat brain slices for neurological and cognitive studies
  • Viable brain tissue for electrophysiology and imaging
  • Consistent sections for drug efficacy testing in brain-related research

With a 5-year warranty, the VF-510-0Z ensures long-term reliability for rat brain tissue sectioning in research and clinical settings.

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RF 1000 Front Right Angle
RF 1000 Front Left Angle
RF 1000 Front
RF 1000 Cutting Stage Front
RF 1000 Foot Press
RF 1000 Cutting Stage Front Left

Rotary Microtome RF-1000

Fully Automated Microtome for Thin Rat Brain Tissue Sections

The RF-1000 rotary microtome offers precision in cutting thin, uniform sections of rat brain tissue. This model is essential for immunohistochemical staining and high-resolution imaging, allowing researchers to study the fine structures of the brain and other organs in detail.

  • Precision-cut rat brain slices for neurological and cognitive studies
  • Viable brain tissue for electrophysiology and imaging
  • Consistent sections for drug efficacy testing in brain-related research

With a 3-year warranty, the RF-1000 provides precise and reproducible thin sectioning for rat brain research.

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6100-right-hand-wheel
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Cryostat CF-6100

Cryostat for Frozen Sectioning of Rat Brain Tissue

The CF-6100 cryostat is specifically designed for frozen sectioning of rat brain tissues, ensuring that OCT-embedded brain samples remain intact during sectioning. It is crucial for preparing frozen brain sections for immunohistochemistry, histopathology, and advanced imaging techniques in brain research.

Experimental Applications Include:

  • Frozen rat brain tissue sections for neurological research and imaging
  • Consistent frozen brain slices for immunohistochemical staining
  • Reliable performance for frozen sectioning of brain tissues in long-term studies

Acting as a laboratory workhorse, the CF-6100 provides dependable frozen sectioning of rat brain tissues for neuroscience and biomedical research.

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Paraffin Dispenser Cold plate
Paraffin Dispenser spout
Paraffin Dispenser foot pedal
Paraffin Dispenser front left

TEC-200 Tissue Embedding Center

Efficient Tissue Processing for Rat Tissue Slicing

The TEC-200 Tissue Embedding Center is designed for seamless embedding. It offers automation for precise and consistent results. Ideal for rat tissue slicing, its ergonomic design ensures operator comfort. Experience stability and precision cutting, and elevate your tissue processing with the TEC-200 from Precisionary Instruments.

  • Intuitive controls
  • Fully programmable ON/OFF control allows automatic system start and stop.
  • Large drain holes that allow easy drainage into trays under all working areas
  • Trimming plates on both sides, as well as a separate heated and cooling workstation, allow easy workflow
  • Simple maintenance and repair in case of a malfunction

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References

Fennell AM, Pitts EG, Sexton LL, Ferris MJ. Phasic Dopamine Release Magnitude Tracks Individual Differences in Sensitization of Locomotor Response following a History of Nicotine Exposure. Sci Rep. 2020 Jan 13;10(1):173. PMID: 31932634; PMCID: PMC6957501. 

Huang W, Zuo W, Chen L, Wang L, Tewfik G, Fu R, Zheng J, Li D, Ye JH. Acetaldehyde Excitation of Lateral Habenular Neurons via Multiple Cellular Mechanisms. J Neurosci. 2021 Sep 8;41(36):7532-7545. Epub 2021 Jul 29. PMID: 34326141; PMCID: PMC8425984.

Werner CT, Mitra S, Auerbach BD, Wang ZJ, Martin JA, Stewart AF, Gobira PH, Iida M, An C, Cobb MM, Caccamise A, Salvi RJ, Neve RL, Gancarz AM, Dietz DM. Neuroadaptations in the dorsal hippocampus underlie cocaine seeking during prolonged abstinence. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26460-26469. Epub 2020 Oct 5. PMID: 33020308; PMCID: PMC7585028.

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