What is Electrophysiology? Electrophysiology is the study of the electrical properties of biological cells and tissues. Specifically, in neuroscience, it includes the measurements of the electrical activity of brain cells, including neurons and their action potential activity. In order to take these measurements, the patch-clamp technique is widely used. In order to measure the electrical […]
What Precisionary Instruments Provides At Precisionary Instruments, we understand that changing processes can seem unlikely favorable, or even nerve-wracking. However, our Scientific team has developed many protocols for sectioning an array of tissue types with the Compresstome® vibratome. Find protocols under the “Information & Support” tab on our website. We provide: Fixed AND fresh brain […]
A Social Network for Scientists Described by the New York Times as a “mashup of Facebook, Twitter, and LinkedIn”, ResearchGate is a social network bringing together academics from around the globe. The media may focus on the big guns of the tech world, but quietly now Researchgate has become an instrumental tool for scientists around […]
We started in 2004 with the very first Compresstome® vibratome. More than a decade later, we bring you our newest member of the Compresstome® vibratome family: The VF-310-0Z! Learning from YOU, our customers! In developing our newest model, we’ve learned a lot by listening directly from our customers. Over those years we’ve been listening to […]
Leaders in the Field of Neuroscience Often heralded as leaders in the field, the Allen Brain institute performs pioneering research on all manner of brain tissue. Working with brain tissue can often be as frustrating as it is rewarding. Slicing brain tissue presents many challenges. The tissue is a combination of soft and fibrous regions. […]
Difficulties of Slicing Older Animal Brains Younger rodent brains are much softer and easier to slice because these brains are not heavily myelinated. With older rodent brains, the amount of myelination makes tissue slicing difficult. Together with labs at the Allen Institute, we have developed the Compresstome to be successful at cutting brains from mature […]
Visit Us at SFN Society for Neuroscience (SfN) is the largest neuroscience society in the world. This year, the SfN conference will be held in San Diego, CA between November 3rd – 7th, and Precisionary Instruments will be in Booth #2737 showcasing the newest Compresstome® vibratomes. Why does Precisionary Instruments Attend SfN? Each year, Precisionary […]
Do you need coring tools for research? If you work with precision-cut tissue, then chances are you need coring tools for tissue slice prep! Many of our customers have asked for coring tools, and we are delighted to announce that Precisionary Instruments now offers coring tools in a wide variety of diameters! Used to prepare […]
During your experiments, have you wanted to take images of each slice before they are cut? We now have a block-face imaging camera system for the Compresstome vibratome that capture slice-by-slice images as you make tissue sections. Shown above are mouse brain slices being cut, with individual images taken after each slice. Working in collaboration […]
We are Here to Support Your Research We’ve all worked on something and hit a road block, right? When this happens, do you receive the answers you need right away? In the scientific community, colleagues are busy, user manuals are misplaced or really lengthy, and finding the answer you need can be downright frustrating. That’s […]