Recommended Model/s

Not sure which model is right for your needs?

Real lab examples

Play Video

Genetic Manipulation of the Mouse Developing Hypothalamus Through In Utero Electroporation

Researchers have used the Compresstome® in their procedure to section mouse embryo hypothalamus that has been injected with DNA and electroporated. This procedure demonstrates how it is possible to transfect nuclei in the hypothalamus region which are less accessible than those in superficial regions. Following this procedure additional experiments can be performed such as immunohistochemistry and in situ hybridization.

Play Video

Lipophilic dye, in situ Hybridization, Immunohistochemistry, and Histology

Explore how scientists use the Compresstome® vibrating microtome to create tissue slices that combine lipophilic dye tracing, whole mount in situ hybridizationimmunohistochemistry, and histology to extract the maximal possible amount of data.


Haddad-Tóvolli R, Heide M, Zhou X, Blaess S, Alvarez-Bolado G. Mouse thalamic differentiation: gli-dependent pattern and gli-independent prepattern. Front Neurosci. 2012 Feb 22;6:27. PMID: 22371696; PMCID: PMC3283895. Download PDF

Li S, Folkvord JM, Rakasz EG, Abdelaal HM, Wagstaff RK, Kovacs KJ, Kim HO, Sawahata R, MaWhinney S, Masopust D, Connick E, Skinner PJ. Simian Immunodeficiency Virus-Producing Cells in Follicles Are Partially Suppressed by CD8+ Cells In Vivo. J Virol. 2016 Nov 28;90(24):11168-11180. PMID: 27707919; PMCID: PMC5126374. Download PDF

Mylvaganam GH, Rios D, Abdelaal HM, Iyer S, Tharp G, Mavinger M, Hicks S, Chahroudi A, Ahmed R, Bosinger SE, Williams IR, Skinner PJ, Velu V, Amara RR. Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1976-1981. PMID: 28159893; PMCID: PMC5338410. Download PDF

See more

Call Now Button617-682-0586