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APPLICATIONS | ORGANS

Tissue Sectioning Solutions for Eye and Retina Research

Create healthy, precise tissue slices from eye samples for studying ocular health and vision using Precisionary Instruments’ vibratome, rotary microtome, and cryostat.

High-Quality Eye Tissue Slices for Vision Research and Ocular Disease Studies

Research involving eye tissue, such as the mouse retina and cow eyes, is crucial for understanding vision, eye diseases, and overall ocular health. Precise, healthy tissue slices are essential for examining ocular structures, cellular compositions, and disease-related changes accurately. 

Precisionary Instruments’ Compresstome VF-510-0Z vibratome allows researchers to obtain live, healthy tissue slices for advanced studies of vision and eye function. The RF-1000 rotary microtome and CF-6100 cryostat provide thin, consistent sections ideal for histological staining and analysis of ocular pathologies. These tools offer precise sectioning solutions for advancing research in vision disorders and eye treatments.

Compresstome® VF-510-0Z

Rapid, High-Viability Sectioning for Electrophysiology

The Compresstome® VF-510-0Z is specifically designed to produce healthy, viable acute brain slices for electrophysiology applications. Its fully automated system enables rapid, precise sectioning that increases neuron viability, making it ideal for patch clamping and other electrophysiological studies. Experimental applications include:

With a 5-year warranty, the VF-510-0Z ensures precise, rapid sectioning to support the highest quality results in electrophysiology, preserving the health of brain tissue and neurons.

Rotary Microtome RF-1000

Fully Automated Microtome for Thin Eye Tissue Sections

The RF-1000 rotary microtome provides thin, uniform sections of eye tissue for detailed histological studies. Its fully automated system is ideal for producing sections for H&E staining, immunohistochemistry, and microscopic imaging of ocular structures.
Experimental applications include:

With a 3-year warranty, the RF-1000 delivers precise, reproducible sectioning for eye tissue research.

Cryostat CF-6100

Cryostat for Frozen Sectioning of Cardiac Tissue

The CF-6100 cryostat is designed for frozen sectioning of cardiac tissue, ensuring the preservation of tissue integrity while producing thin sections for histology and imaging studies.

Experimental applications include:

Acting as a laboratory workhorse, the CF-6100 ensures reliable frozen sectioning for heart tissue studies over time.

TEC-200 Tissue Embedding Center

Efficient Tissue Processing for Eye and Retina Research

The TEC-200 Tissue Embedding Center is designed for seamless embedding. It offers automation for precise and consistent results. Ideal for eye and retina research, its ergonomic design ensures operator comfort. Experience stability and precision cutting, and elevate your tissue processing with the TEC-200 from Precisionary Instruments.

References

Bose SK, White BM, Kashyap MV, Dave A, De Bie FR, Li H, Singh K, Menon P, Wang T, Teerdhala S, Swaminathan V, Hartman HA, Jayachandran S, ChandrasekaranP, Musunuru K, Jain R, Frank DB, Zoltick P, Peranteau WH. In utero adenine base editing corrects multi-organ pathology in a lethal lysosomal storage disease. Nat Commun. 2021 Jul 13;12(1):4291. PMID: 34257302; PMCID: PMC8277817.

Lewis TR, Shores CR, Cady MA, Hao Y, Arshavsky VY, Burns ME. The F220C and F45L rhodopsin mutations identified in retinitis pigmentosa patients do not cause pathology in mice. Sci Rep. 2020 May 5;10(1):7538. PMID: 32371886; PMCID: PMC7200662.

Rochon PL, Theriault C, Rangel Olguin AG, Krishnaswamy A. The cell adhesion molecule Sdk1 shapes assembly of a retinal circuit that detects localized edges. Elife. 2021 Sep 21;10:e70870. PMID: 34545809; PMCID: PMC8514235.

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