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Tissue Sectioning Solutions for Tumor Studies

Create healthy, viable tumor tissue slices for oncology and cancer research using Precisionary Instruments’ advanced sectioning tools.

Get High-Quality Tumor Tissue Slices

Tumor tissue sectioning is essential for cancer research, helping scientists study tumor growth, metastasis, and drug responses. Thin, flat tissue sections allow researchers to investigate cellular and molecular changes in tumors and evaluate the effectiveness of therapeutic interventions. High-quality tissue slices are critical for studying cancers in various organs, including lung, liver, brain, and breast tissues.

Our vibratomes are widely used in tumor models to generate fresh and viable slices for drug screening, personalized medicine, and tumor microenvironment studies. These sections also enable researchers to explore tumor-immune interactions, angiogenesis, and response to immunotherapies.

Tissue sectioning is essential to study the immune functions of lymph nodes, providing thin, flat samples for microscopic observation. These tissue sections allow researchers to explore processes like antigen presentation, T cell activation, and antibody production. Lymph node tissue research is vital in understanding lymphatic disorders, such as lymphoma and lymphedema, and plays a key role in cancer immunotherapy and infectious disease research.

Compresstome® VF-510-0Z

Precision Vibrating Microtome for Tumor Tissue Slices

The VF-510-0Z provides precise and consistent tumor tissue slices, maintaining viability for longer than other slicers. It is ideal for cancer research applications requiring fresh tumor slices for drug testing and tumor microenvironment studies.

Applications Include:

With a 5-year warranty, the VF-510-0Z delivers reliable performance for tumor sectioning in research laboratories.

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Compresstome® VF-800-0Z

High-Throughput Vibrating Microtome for Tumor Tissue Slices

The VF-800-0Z is optimized for large tumor tissue samples, providing high-throughput sectioning for labs with demanding workflows. It supports both fresh and fixed tissue sectioning, making it ideal for large-scale drug screening and clinical research.

Applications Include:

With a 5-year warranty, the VF-800-0Z ensures rapid, consistent sectioning for large tumor samples in cancer research.

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Rotary Microtome RF-1000

Fully Automated Microtome for Thin Tumor Tissue Sections

The RF-1000 rotary microtome offers precision in cutting thin sections of tumor tissues. It is essential for immunohistochemistry and high-resolution imaging, allowing detailed histological analysis of cancer cells and tumor structures.

Applications Include:

With a 3-year warranty, the RF-1000 ensures precise and reproducible sectioning for tumor tissue research.

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Cryostat CF-6100

Cryostat for Frozen Sectioning of Tumor Tissue

The CF-6100 cryostat enables frozen sectioning of tumor tissues, preserving the integrity of OCT-embedded samples. It is essential for advanced imaging and immunohistochemical staining, supporting research on metastasis and tumor immune interactions.

Applications Include:

Acting as a laboratory workhorse, the CF-6100 provides dependable frozen sectioning for cancer research.

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TEC-200 Tissue Embedding Center

Efficient Tissue Processing for Tumor Studies

The TEC-200 Tissue Embedding Center is designed for seamless embedding. It offers automation for precise and consistent results. Ideal for tumor studies, its ergonomic design ensures operator comfort. Experience stability and precision cutting, and elevate your tissue processing with the TEC-200 from Precisionary Instruments.

Intuitive controls
Fully programmable ON/OFF control allows automatic system start and stop.
Large drain holes that allow easy drainage into trays under all working areas
Trimming plates on both sides, as well as a separate heated and cooling workstation, allow easy workflow
Simple maintenance and repair in case of a malfunction

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Real Labs Trust Precisionary Vibratomes for Tumor Slicing

Advancing Functional Precision Medicine with the Compresstome® Vibratome

Dr. Andrew Satterlee is pioneering the use of organotypic brain slice cultures (OBSC) to accelerate drug testing for cancer treatment. In this webinar, Dr. Satterlee explains how the Compresstome® vibratome plays a critical role in maintaining patient tumor tissues ex vivo, enabling precise therapeutic testing and advancing personalized medicine research.

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3D Lineage Tracing in Tumorigenesis with Precision Tissue Sections Using the Compresstome® Vibratome

Dr. Snyder, from Duke University, uses the Compresstome® vibratome to create precision-cut tumor tissue sections for studying early cancer development. In this webinar, Dr. Snyder highlights how the Compresstome® enables 3D lineage tracing during tumorigenesis, providing crucial insights into genetic heterogeneity and the spatial dynamics of tumor initiation.

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Studying Cell Motility in Glioblastoma with Precision-Cut Brain Sections

Dr. Natanael Zarco, a Research Associate at Mayo Clinic, uses the Compresstome® vibratome to prepare precision-cut brain sections for studying glioblastoma cell migration. In this webinar, Dr. Zarco explores how these sections enable his research into how glioblastoma stem cells invade brain regions, providing critical insights into cancer progression and potential therapeutic targets.

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Exploring Lung Cancer with Live Tumor Slice Cultures Using the Compresstome® Vibratome

Dr. Tsilingiri is working on tumor immunotherapy and using the Compresstome vibrating microtome to examine the interaction between tumor tissues and autologous lymph node cells in slice cultures. This work is being carried out in the frame of an EU-funded Consortium, Tumour-LNoC (Tumour-Lymph node on a chip), with the ultimate goal of mimicking the metastatic process on a chip and monitor metastasizing cells in real time.

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Tumor Slicing References

Hu KH, Eichorst JP, McGinnis CS, Patterson DM, Chow ED, Kersten K, Jameson SC, Gartner ZJ, Rao AA, Krummel MF. ZipSeq: barcoding for real-time mapping of single cell transcriptomes. Nat Methods. 2020 Aug;17(8):833-843. Epub 2020 Jul 6. PMID: 32632238; PMCID: PMC7891292.

Li S, Folkvord JM, Kovacs KJ, Wagstaff RK, Mwakalundwa G, Rendahl AK, Rakasz EG, Connick E, Skinner PJ. Low levels of SIV-specific CD8+ T cells in germinal centers characterizes acute SIV infection. PLoS Pathog. 2019 Mar 21;15(3):e1007311. PMID: 30897187; PMCID: PMC6445460.

Webb GM, Li S, Mwakalundwa G, Folkvord JM, Greene JM, Reed JS, Stanton JJ, Legasse AW, Hobbs T, Martin LD, Park BS, Whitney JB, Jeng EK, Wong HC, Nixon DF, Jones RB, Connick E, Skinner PJ, Sacha JB. The human IL-15 superagonist ALT-803 directs SIV-specific CD8+ T cells into B-cell follicles. Blood Adv. 2018 Jan 23;2(2):76-84. PMID: 29365313; PMCID: PMC5787870.

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Bring greater precision and consistency to your lymph node tissue slices. Fill out the form to request a quote from Precisionary Instruments. We’ll respond within one business day.

Tissue Sectioning Solutions for Tumor Studies

Get High-Quality Tumor Tissue Slices

Precision Vibrating Microtome for Tumor Tissue Slices

High-Throughput Vibrating Microtome for Tumor Tissue Slices

Fully Automated Microtome for Thin Tumor Tissue Sections

Cryostat for Frozen Sectioning of Tumor Tissue

Efficient Tissue Processing for Tumor Studies

Real Labs Trust Precisionary Vibratomes for Tumor Slicing

Advancing Functional Precision Medicine with the Compresstome® Vibratome

3D Lineage Tracing in Tumorigenesis with Precision Tissue Sections Using the Compresstome® Vibratome

Studying Cell Motility in Glioblastoma with Precision-Cut Brain Sections

Exploring Lung Cancer with Live Tumor Slice Cultures Using the Compresstome® Vibratome

Tumor Slicing References

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