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Compresstome® Vibrating Microtomes

Our Compresstome® tissue slicer is a vibrating microtome that uses a high-frequency oscillating cutting blade to help you slice through tissue to get sections for research and clinical use.

How it works

Key benefits

Other tissue slicers on the market will have a flat stage where you glue your tissue sample, with a cutting blade that approaches horizontally. However, the blade can easily push your tissue sample and squish, tilt, and compress it — all of these effects may damage cells and tissue architecture.
Embedding tissue in agarose is simple and proven to keep the tissue from harm. The agarose helps stabilize the tissue during cutting with the Compresstome®. This yields slices with smooth surfaces, and does not harm or disrupt the tissue. Agarose embedding allows you to cut consistent, even tissue slices without chatter marks.
The Compresstome® vibrating microtome has been scientifically demonstrated to create more consistent tissue sections for immunohistochemistry and electrophysiology compared to other vibratomes. Here, you can see the significant reduction in chattermarks in tissues slices produced with our Compresstome® tissue slicer versus sections (A, C). Slices made at the same cutting speed and oscillation on another market vibratome produces chattermarks on the surface of tissue slices.

Comparison of tissue slices sectioned with a Compresstome® vibrating microtome vs. another leading market vibratome.

Key benefits

Other tissue slicers on the market will have a flat stage where you glue your tissue sample, with a cutting blade that approaches horizontally. However, the blade can easily push your tissue sample and squish, tilt, and compress it — all of these effects may damage cells and tissue architecture.
Embedding tissue in agarose is simple and proven to keep the tissue from harm. The agarose helps stabilize the tissue during cutting with the Compresstome®. This yields slices with smooth surfaces, and does not harm or disrupt the tissue. Agarose embedding allows you to cut consistent, even tissue slices without chatter marks.
The Compresstome® vibrating microtome has been scientifically demonstrated to create more consistent tissue sections for immunohistochemistry and electrophysiology compared to other vibratomes. Here, you can see the significant reduction in chattermarks in tissues slices produced with our Compresstome® tissue slicer versus sections (A, C). Slices made at the same cutting speed and oscillation on another market vibratome produces chattermarks on the surface of tissue slices.
Comparison of tissue slices sectioned with a Compresstome® vibrating microtome vs. another leading market vibratome.

WHAT SETS PRECISIONARY MICROTOMES APART

Agarose embedding

Agarose embedding is the process of embedding your tissue sample with agarose solution before you cut tissue slices with the Compresstome© vibratome. It takes only a fraction of the user’s time for sectioning overall and aids in the production of healthier and smoother tissue slides.

Auto zero-Z® technology

These vibrating heads are precisely aligned to eliminate vibrations in the Z-axis. Auto Zero-Z® technology helps reduce damage to surface cells on live tissue samples, and further reduce chattermarks on thin sections for improved imaging results

Best-in-class customer service

Experience unparalleled customer service with fast response times. Our dedicated team supports scientists and clinicians, ensuring successful research for years to come.

Agarose embedding is the process of embedding your tissue sample with agarose solution before you cut tissue slices with the Compresstome© vibratome. It takes only a fraction of the user's time for sectioning overall and aids in the production of healthier and smoother tissue slides.

These vibrating heads are precisely aligned to elimate vibrations in the Z-axis. Auto Zero-Z® technology helps reduce damage to surface cells on live tissue samples, and further reduce chattermarks on thin sections for improved imaging results

Models (4)

New

VF-510-0Z

Fully automated

Top Applications

Minimum slice thickness

10 µm

Cutting mode

Automatic

Slice thickness adjustment

Automatic

Available specimen tube sizes

15.5mm, 20mm

Includes Auto Zero-Z technology

✓

VF-210-0Z

Semi-automated, manual thickness advance

Top Applications

Minimum slice thickness

20 µm

Cutting mode

Automatic

Slice thickness adjustment

Manual

Available specimen tube sizes

15.5mm, 20mm

Includes Auto Zero-Z technology

✓

VF-300

Fully automated

Top Applications

Minimum slice thickness

10 µm

Cutting mode

Automatic

Slice thickness adjustment

Automatic

Available specimen tube sizes

15.5mm, 20mm

Includes Auto Zero-Z technology

no: No

VF-800-0Z

Large diameter vibratome, for humans, primates, whole organs

Top Applications

Minimum slice thickness

40 µm

Cutting mode

Automatic

Slice thickness adjustment

Automatic

Available specimen tube sizes

100mm

Includes Auto Zero-Z technology

✓

VF-510-0Z

Fully automated

Top Applications

New

Model	Min. slice thickness	Cutting mode	Slice thickness adjustment	Available specimen tube sizes	Includes Auto Zero-Z technology
VF-510-0Z	10 µm	Automatic	Automatic	15.5mm, 20 mm	✓
VF-210-0Z	20 µm	Automatic	Manual	15.5mm, 20 mm	✓
VF-800-0Z	40 µm	Automatic	Automatic	100mm	✓
VF-300	10 µm	Automatic	Automatic	15.5mm, 20 mm	No