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Compresstome® Vibrating Microtomes

Our Compresstome® tissue slicer is a vibrating microtome that uses a high-frequency oscillating cutting blade to help you slice through tissue to get sections for research and clinical use.

How it works

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Key benefits

  • Other tissue slicers on the market will have a flat stage where you glue your tissue sample, with a cutting blade that approaches horizontally. However, the blade can easily push your tissue sample and squish, tilt, and compress it — all of these effects may damage cells and tissue architecture.
  • Embedding tissue in agarose is simple and proven to keep the tissue from harm. The agarose helps stabilize the tissue during cutting with the Compresstome®. This yields slices with smooth surfaces, and does not harm or disrupt the tissue. Agarose embedding allows you to cut consistent, even tissue slices without chatter marks.
  • The Compresstome® vibrating microtome has been scientifically demonstrated to create more consistent tissue sections for immunohistochemistry and electrophysiology compared to other vibratomes. Here, you can see the significant reduction in chattermarks in tissues slices produced with our Compresstome® tissue slicer versus sections (A, C). Slices made at the same cutting speed and oscillation on another market vibratome produces chattermarks on the surface of tissue slices.
Comparison of tissue slices sectioned with a Compresstome® vibrating microtome vs. another leading market vibratome.

Key benefits

  • Other tissue slicers on the market will have a flat stage where you glue your tissue sample, with a cutting blade that approaches horizontally. However, the blade can easily push your tissue sample and squish, tilt, and compress it — all of these effects may damage cells and tissue architecture.

  • Embedding tissue in agarose is simple and proven to keep the tissue from harm. The agarose helps stabilize the tissue during cutting with the Compresstome®. This yields slices with smooth surfaces, and does not harm or disrupt the tissue. Agarose embedding allows you to cut consistent, even tissue slices without chatter marks.
  • The Compresstome® vibrating microtome has been scientifically demonstrated to create more consistent tissue sections for immunohistochemistry and electrophysiology compared to other vibratomes. Here, you can see the significant reduction in chattermarks in tissues slices produced with our Compresstome® tissue slicer versus sections (A, C). Slices made at the same cutting speed and oscillation on another market vibratome produces chattermarks on the surface of tissue slices.
    Comparison of tissue slices sectioned with a Compresstome® vibrating microtome vs. another leading market vibratome.

WHAT SETS PRECISIONARY MICROTOMES APART

Agarose embedding is the process of  embedding your tissue sample with agarose solution before you cut tissue slices with the Compresstome© vibratome. It takes only a fraction of the user’s time for sectioning overall and aids in the production of healthier and smoother tissue slides.

These vibrating heads are precisely aligned to eliminate vibrations in the Z-axis. Auto Zero-Z® technology helps reduce damage to surface cells on live tissue samples, and further reduce chattermarks on thin sections for improved imaging results

Experience unparalleled customer service with fast response times. Our dedicated team supports scientists and clinicians, ensuring successful research for years to come.

Agarose embedding is the process of  embedding your tissue sample with agarose solution before you cut tissue slices with the Compresstome© vibratome. It takes only a fraction of the user's time for sectioning overall and aids in the production of healthier and smoother tissue slides.
These vibrating heads are precisely aligned to eliminate vibrations in the Z-axis. Auto Zero-Z® technology helps reduce damage to surface cells on live tissue samples, and further reduce chattermarks on thin sections for improved imaging results
These vibrating heads are precisely aligned to elimate vibrations in the Z-axis. Auto Zero-Z® technology helps reduce damage to surface cells on live tissue samples, and further reduce chattermarks on thin sections for improved imaging results

Models (4)

Semi-automated, manual thickness advance

Top Applications

Fully automated

Top Applications

Large diameter vibratome, for humans, primates, whole organs

Top Applications

ModelMin. slice thicknessCutting modeSlice thickness adjustmentAvailable specimen tube sizesIncludes Auto Zero-Z technology
VF-510-0Z
10 µmAutomaticAutomatic15.5mm, 20 mm
VF-210-0Z
VF-210 Semi-automated
20 µmAutomaticManual15.5mm, 20 mm
VF-800-0ZVF-800-0Z Front View40 µmAutomaticAutomatic100mm
VF-300
10 µmAutomaticAutomatic15.5mm, 20 mmNo
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