Slicing the Spinal Cord

How do I embed and cut great spinal cord slice?

You asked, and we listened! We realized that embedding spinal cord tissue for cutting slices is quite difficult. Working with our biomedical illustrator, we came up with this visual protocol to help you embed spinal cord for cutting:

How about some spinal cord references?

You got it! If you would like to explore peer-reviewed publications from labs that have used the Compresstome vibrating microtome to cut spinal cord tissue slices, check these out:

• Spinal Cord Injury Results in Chronic Mechanical Stiffening (Cooper JG et al)
• Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST (Nakano Y et al.)
• h-Channels Contribute to Divergent Intrinsic Membrane Properties of Supragranular Pyramidal Neurons in Human versus Mouse Cerebral Cortex (Kalmbach BE et al.)
• Methods Used for Studying TRP Channel Functions in Sensory Neurons (Premkumar LS et al.)