Simplify your tissue sectioning. Preserve integrity. Eliminate freezing artifacts.
Traditional cryostats have long been the go-to tool for tissue sectioning, but they come with significant drawbacks—freezing damage, bulky design, and intensive maintenance. The Compresstome VF-510-0Z offers a modern alternative: a next-generation vibrating microtome that enables fast, reliable sectioning of live or fixed tissues—without the need for freezing.
Whether you’re preparing brain slices for electrophysiology, creating organotypic slice cultures, or performing drug screening on delicate samples, the Compresstome ensures consistent, high-quality results with minimal setup time.
The Cryostat Problem
Cryostats are effective for frozen histology but introduce several challenges that limit their usefulness for live or delicate tissues:
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Freezing damages tissue structure and viability, introducing artifacts that compromise data.
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High maintenance requirements due to compressors and frost buildup.
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Large footprint, making them difficult to fit into modern lab spaces.
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Limited flexibility across experimental applications.
These limitations often lead to inconsistent results, increased downtime, and wasted samples—especially in workflows that rely on maintaining tissue viability.
The Compresstome Solution
The Compresstome VF-510-0Z eliminates the need for freezing entirely, preserving both cell viability and tissue morphology. It offers a flexible, user-friendly solution for a wide range of research applications.
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No freezing required → Preserved viability and structure
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Variable thickness from 4–1000 μm for diverse workflows
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Compact desktop footprint → easily integrates into any lab setup
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Low maintenance, high reliability
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Backed by a 5-year warranty and expert technical support
Researchers benefit from a smoother slicing process, better data quality, and more time focused on science—not maintenance.
Side-by-Side Comparison
| Feature | Cryostat | Compresstome VF-510-0Z |
|---|---|---|
| Section Thickness | 0.5–100 μm | 4–1000 μm |
| Tissue Viability | Destroyed by freezing | Fully preserved |
| Ease of Use | Steep learning curve | Intuitive, minimal training |
| Maintenance | High (compressor, frost) | Low |
| Space Requirements | Large floor space | Compact desktop |
| Warranty | 1–2 years typical | 5 years |
| Demo Options | Rarely available | Rental, Virtual, or On-site |
| Applications | Frozen histology, IHC | Electrophysiology, Tumor Slices, Organoids, Slice Culture, IHC, Imaging |
See the Difference
Compresstome Cryostat
Preserved Integrity Freezing Damage
When tissue quality and experimental precision matter, researchers are moving toward the Compresstome for a reason—it delivers cleaner slices, healthier tissues, and reproducible data across experiments.
Curious How It Compares in Your Workflow?
Our scientific team can walk you through how the Compresstome fits your specific research needs. Schedule a personalized demo or connect with us today:
📧 [email protected]
🌐 www.precisionary.com
📞 (617) 682-0586