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APPLICATIONS | EXPERIMENTS

Tissue Sectioning Solutions for Electron Microscopy

Create ultra-thin, consistent sections for electron microscopy with Precisionary Instruments’ vibratomes and microtomes

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Electron microscopy
Electron microscopy

Achieve Precise Tissue Sections for Electron Microscopy

Electron microscopy (EM) requires ultra-thin tissue sections to ensure the generation of high-resolution images. To meet the demands of EM, tissue sections must be consistently thin and smooth to avoid artifacts and distortion in the images.

Precisionary Instruments’ vibratomes and microtomes are designed to produce the ultra-thin, uniform sections needed for reliable EM imaging, ensuring optimal clarity and detail in every sample.

VF-510-0Z_2a
VF-510-0Z_1a
VF-510-0Z_3a
VF-510-0Z_4a
VF-510-0Z_5a
VF-510-0Z_6a
VF-510-0Z_7a
VF-510-0Z_8a

Compresstome® VF-510-0Z

Ultra-Precise Vibrating Microtome for Electron Microscopy

Our most popular vibratome model, the Compresstome® VF-510-0Z, is designed to deliver consistent, ultra-thin sections for electron microscopy. This fully automated system features precision stabilizers, ensuring repeatable, high-quality cuts with every use. Experimental applications include:

  • Consistent, thin sectioning for electron microscopy
  • Preservation of fine tissue structure for high-resolution imaging
  • Reproducible slices for ultrastructural studies
  • Mouse brain slices for electrophysiology and optogenetics
  • Fresh slices for organotypic culture and tumor research
  • Thin fixed sections for IHC and ISH

With a 5-year warranty, the Compresstome VF-510-0Z offers unmatched reliability and precision for demanding microscopy applications.

VIEW SPECS

RF 1000 Front Right Angle
RF 1000 Cutting Stage Front Left
RF 1000 Cutting Stage Front
RF 1000 Foot Press
RF 1000 Front
RF 1000 Front Left Angle
RF 1000 Knife Holder Cutting Stage
RF 1000 Knife Holder Set Knob
RF 1000 Specimen Clamp

ROTARY MICROTOME RF-1000

Fully Automated Microtome for Electron Microscopy

The RF-1000 rotary microtome is ideal for producing ultra-thin, consistent sections required for electron microscopy. This fully automated system ensures the finest control over section thickness, making it perfect for detailed ultrastructural analysis. Experimental applications include:

  • Ultra-thin sectioning for electron microscopy
  • Precise tissue slicing for high-resolution cellular imaging
  • Consistent, repeatable cuts for molecular and ultrastructural studies
  • Used for EM, SEM, TEM and more

With a 3-year warranty, the RF-1000 delivers precision and reliability for demanding electron microscopy applications.

VIEW SPECS

tec-main
Paraffin Dispenser Cold plate
Paraffin Dispenser spout
Paraffin Dispenser foot pedal
Paraffin Dispenser front left

TEC-200 Tissue Embedding Center

Efficient Tissue Processing for Electron Microscopy

The TEC-200 Tissue Embedding Center is designed for seamless embedding. It offers automation for precise and consistent results. Ideal for electron microscopy, its ergonomic design ensures operator comfort. Experience stability and precision cutting, and elevate your tissue processing with the TEC-200 from Precisionary Instruments.

  • Intuitive controls
  • Fully programmable ON/OFF control allows automatic system start and stop.
  • Large drain holes that allow easy drainage into trays under all working areas
  • Trimming plates on both sides, as well as a separate heated and cooling workstation, allow easy workflow
  • Simple maintenance and repair in case of a malfunction

VIEW SPECS

References

Kamari Y, Cohen H, Shaish A, Bitzur R, Afek A, Shen S, Vainshtein A, Harats D. Characterisation of atherosclerotic lesions with scanning electron microscopy (SEM) of wet tissue. Diab Vasc Dis Res. 2008 Mar;5(1):44-7. doi: 10.3132/dvdr.2008.008. PMID: 18398812.

Kim Y, Jang YN, Kim JY, Kim N, Noh S, Kim H, Queenan BN, Bellmore R, Mun JY, Park H, Rah JC, Pak DTS, Lee KJ. Microtubule-associated protein 2 mediates induction of long-term potentiation in hippocampal neurons. FASEB J. 2020 May;34(5):6965-6983. doi: 10.1096/fj.201902122RR. Epub 2020 Apr 1. PMID: 32237183.

Friedrichsen K, Ramakrishna P, Hsiang JC, Valkova K, Kerschensteiner D, Morgan JL. Reconstructing neural circuits using multiresolution correlated light and electron microscopy. Front Neural Circuits. 2022 Oct 21;16:753496. doi: 10.3389/fncir.2022.753496. PMID: 36338333; PMCID: PMC9635852.

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Bring greater precision and consistency to your electron microscopy experiments. Fill out the form to request a quote from Precisionary Instruments. We’ll respond within one business day.

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