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Tissue Slicing Solutions for Whole Organ Sectioning

Reduce variability and enhance reliability when sectioning large samples and whole organs with Precisionary Instruments’ large-diameter vibratomes.

Large Sample Sectioning Made Simple

Large sample sectioning involves cutting entire organs or large tissues rather than small fragments. This method allows researchers to study the three-dimensional architecture of tissues, the distribution and organization of cells, and the relationships between cellular components. It is essential in various fields, from studying tumor development and disease effects on organs to advancing tissue engineering.

Precisionary Instruments’ large-diameter vibratomes are specifically designed to handle whole organs and large polymers, offering precise, consistent sections that support detailed analysis. Whether you’re investigating disease progression or developing innovative treatments, our vibratomes make large sample sectioning both simple and reliable.

Compresstome® VF-800-0Z

Precision Sectioning for Whole Organs and Large Samples

The Compresstome® VF-800-0Z is a fully-automated vibrating microtome designed for whole organ and large sample sectioning. With its large diameter slicing capability, the VF-800-0Z can embed and section entire organs or large tissue samples, making it ideal for applications where studying full tissue architecture is critical. Experimental applications include:

Backed by a 5-year warranty, the VF-800-0Z delivers precise, reliable sectioning, making it an essential tool for detailed tissue studies and large sample analysis in cutting-edge research.

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References

Xu F, Shen Y, Ding L, Yang CY, Tan H, Wang H, Zhu Q, Xu R, Wu F, Xiao Y, Xu C, Li Q, Su P, Zhang LI, Dong HW, Desimone R, Xu F, Hu X, Lau PM, Bi GQ. High- throughput mapping of a whole rhesus monkey brain at micrometer resolution. Nat Biotechnol. 2021 Dec;39(12):1521-1528. doi: 10.1038/s41587-021-00986-5. Epub 2021 Jul 26. PMID: 34312500.

Pesce L, Scardigli M, Gavryusev V, Laurino A, Mazzamuto G, Brady N, Sancataldo G, Silvestri L, Destrieux C, Hof PR, Costantini I, Pavone FS. 3D molecular phenotyping of cleared human brain tissues with light-sheet fluorescence microscopy. Commun Biol. 2022 May 12;5(1):447. doi: 10.1038/s42003-022-03390-0. PMID: 35551498; PMCID: PMC9098858.

Yu W, Kang L, Tsang VTC, Zhang Y, Wong IHM, Wong TTW. Translational rapid ultraviolet-excited sectioning tomography for whole-organ multicolor imaging with real-time molecular staining. Elife. 2022 Nov 4;11:e81015. doi: 10.7554/eLife.81015. PMID: 36331195; PMCID: PMC9671503.

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Tissue Slicing Solutions for Whole Organ Sectioning

Large Sample Sectioning Made Simple

Precision Sectioning for Whole Organs and Large Samples

References

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