Upcoming Webinar | May 13 | Organotypic Tumor Slices: A Platform for Identifying Therapeutic Targets in Cancer-Stroma Interactions

Precisionary Rotary Microtomes

Precisionary Instruments offers a full line of high-quality rotary microtomes for histopathology, research, and clinical purposes. Our microtomes give you reliable sections over a range of tissue slice thicknesses.

Rotary Microtomes Perfected

With Precisionary rotary microtomes, researchers can cut thin sections of tissue, down to less than 1µm. Rotary microtomes are ideal for quick and easy high-throughput tissue sectioning, which is great for research needing serial cutting of samples. Rotary microtomes are also great for cutting harder materials like tissue embedded in paraffin-wax, polymers or resins. Every rotary microtome model from Precisionary is easy to operate and clean up making tissue prep a breeze.

 

Top applications

Compresstome® Models

RF 600

RF-600

Our most popular vibratome model. Ultra-precise & consistent.

ROTARY MICROTOME RF-800 Right Angle

RF-800

A semi-automated rotary microtome with manual thickness advance made for ergonomic use.

RF 1000 Front Right Angle

RF-1000

A top-of-the-line, fully-automated rotary microtome made for repetitive tissue slicing.

Compare Specs

Rotary Microtome Model

Microtome Type

Manual

Semi-Automated

Fully Automated

Section Thickness Range

0μm – 60μm adjustable as follows:
0μm – 2μm (in 0.5μm increments)
2μm – 10μm (in 1μm increments)
10μm – 20μm (in 2μm increments)
20μm – 60μm (in 5μm increments)

0-99.9μm (in 0.1 μm increments)

0.5μm – 100μm adjustable as follows:
0.5μm – 5μm (in 0.5μm increments)
5μm – 20μm (in 1μm increments)
20μm – 60μm (in 5μm increments)
60μm – 100μm (in 10μm increments)

Trimming Thickness Range

0μm – 60μm adjustable as follows:
0μm – 2μm (in 0.5μm increments)
2μm – 10μm (in 1μm increments)
10μm – 20μm (in 2μm increments)
20μm – 60μm (in 5μm increments)

0-999μm (in 0.1 μm increments)

5μm – 600μm adjustable as follows:
5μm – 10μm (in 5μm increments)
10μm – 100μm (in 10μm increments)
100μm – 200μm (in 20μm increments)
200μm – 600μm (in 50μm increments)

Minimum Section Thickness

0.5µm

0.1µm

0.5µm

Specimen Retraction

None

0-99μm (Optional on/off)

0-220μm (Optional on/off)

Horizontal Specimen Stroke

23mm

28mm

20mm

Vertical Specimen Stroke

58mm

57mm

60mm

Specimen Head Rotation

7-degrees rotation in X-Y axes

4-degrees rotation in X-Y axes

8-degrees rotation in X-Y axes

Specimen Feed Speed

Coarse handwheel (manual)

Electronically adjustable

Electronically adjustable

Dimensions (L x W x H)

22 in x 16 3⁄4 in x 11 1⁄2 in

22 3⁄4 in x 16 in x 12 9/16 in

19 1⁄2 in x 16 7/8 in x 12 in

Weight

54 lb

67 lb

60 lb

Voltage & Power

None

100-120V, 60Hz

100-120V, 60Hz

Additional Accessories (Included for FREE!)

  • Universal paraffin specimen clamp
  • Box of 50 cutting blades

Box of 50 cutting blades

  • Universal paraffin specimen clamp
  • Foot pedal controller
  • Side control panel
  • Box of 50 cutting blades

FAQs

What are “rotary microtomes?

Rotary microtomes are routinely used for making paraffin-wax embedded tissue sections for histology and pathology. Because they are used for high volume sectioning, rotary microtomes need to be robust.

Precisionary Instruments offers a full line of high quality rotary microtomes for histopathology, research, and clinical purposes. Our microtomes give you reliable sections over a range of tissue slice thicknesses.

What is a rotary microtome and what is it typically used for?

A rotary microtome is a type of microtome that cuts thin sections by moving the sample up and down across a cutting knife. The samples are usually held in a specimen head. The up-and-down movement of the specimen head is controlled by a handwheel—hence that “rotary” name! Rotary microtomes are typically used for cutting tissue samples embedded in paraffin wax. These are usually tissues obtained from surgical biopsies for histopathological analysis. Thus, rotary microtomes are commonly used in histology and pathology studies.

In general, how do I operate a rotary microtome?

To operate a rotary microtome, you would first insert a low-profile or high-profile blade into the blade holder on the knife block. Then, make sure the blade guard is lifted to protect your hands from the blade. Next, insert your paraffin wax cartridge containing your sample into the specimen clamp. Then, you will use either a coarse wheel (in manual models) or press a button (in semi-automatic and automatic models) to advance the specimen clamp toward your knife block. Select the desired thickness of your slices and start sectioning to your desired area.

Does Precisionary offer rotary microtomes for purchase?

Yes, here at Precisionary Instruments, we currently carry three (3) types of rotary microtomes. The RF-600 which is our manual model, the RF-800 which is our semi-automatic model, and the RF-1000 which is our fully automated model. More information on those models can be found below.

What is the difference between the rotary microtome models from Precisionary Instruments?

We carry three (3) types of rotary microtomes. These are the RF-600, RF-800, and RF-1000 models.

  • The RF-600 is a manual model. This means that moving the specimen head forward and backward is done manually. Faster movement can be achieved using a coarse handwheel located on the left hand side of the RF-600 rotary microtome. Cutting movements using the handwheel are also done manually.
  • The RF-800 is a semi-automated rotary microtome. This means that the forward and backward movement of the specimen head can be controlled electronically. You can advance your sample using controls on the LCD screen, and there are fast, slow, and single “click” movements. Cutting movements using the handwheel is done manually.
  • The RF-1000 is a fully automated rotary microtome. This means that movement of the specimen head, as well as cutting, can both be completed electronically and automatically!

There are additional differences in the technical specifications of these 3 rotary microtome models, which you can explore in detail here.

What is the warranty for rotary microtomes from Precisionary Instruments?

We offer a full three (3) year warranty that covers all rotary microtome models. The warranty covers parts, shipping, repairs, and labor fees should there be any defect in the rotary microtome unit that is due to manufacturing. However, the warranty does not cover any defects resulting from improper use.

Do you offer annual service plans or maintenance services for your rotary microtomes?

Yes! We offer an annual service plan that covers your rotary microtome’s maintenance and care after your warranty period ends. The Annual Service Plan comes in two different tiers: 1) Basic Plan, and 2) Premium Plan. Each annual service plan covers all repair labor fees and maintenance costs, including parts, accessories, and shipping fees. Think of the annual plan as providing an extended year of warranty coverage. This helps give you peace of mind!

What consumables will I need to operate the rotary microtome?

There are three different consumables needed to operate your rotary microtome

  • Rotary microtome cutting blades: we offer  Low-Profile cutting blades. Each dispenser box includes 50 individual blades. We send you a free box of blades free with your microtome purchase.
  • Metal molds for tissue preparation: we offer a pack of 12 metal molds for tissue preparation. In the pack, there are three of each size below:
    • 1 cm x 1 cm
    • 2 cm x 2 cm
    • 1.5 cm x 2.5 cm
    • 2.5 cm x 3.8 cm
  • Plastic embedding cassette: we offer rotary microtome plastic cassettes (bottom and lid)

How is a hot water bath used with the rotary microtome for collecting tissue sections?

A hot water bath is essentially a paraffin section flotation bath that helps handle sectioned samples in histology and pathology laboratories. The hot water bath is filled with hot or warm distilled water, which allows for meticulous manipulation of cut tissue sections onto glass slides. These flotation baths are designed to prevent wrinkling and distortion of thin paraffin-wax embedded sections after they are cut and before they are mounted onto glass slides.

What are the components of the knife block?

The knife block comes with 3 components. These components are below:

  • Bottom component: allows for assembly onto microtome base. Slides backwards and forwards.
  • Middle component: allows for blade angle adjustment. We recommend a cutting angle of ~2 degrees for optimal tissue sectioning and collecting histology ribbons.
  • Top component: the cutting stage with the blade guard and blade ejector

Where can I find and buy additional parts and consumables for my rotary microtome?

Additional parts and consumables for rotary microtomes are found here.

They can be purchased via the E-Store on our website or through a purchase order generated from a quote established from a direct email or quote inquiry box found on our website here.

Have More Questions?

Let’s Talk.

Request a

Quote

Take the first step to better tissue sectioning. Fill out the form to request a quote for a rotary microtome. We’ll get back to you within one business day.