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Blog > Publication Highlight: Compresstome Vibratome Proven Superior in Fresh Primate Tissue Sectioning

Publication Highlight: Compresstome Vibratome Proven Superior in Fresh Primate Tissue Sectioning

Published on February 5, 2024

Twenty Years of Vibratome Quality

At Precisionary Instruments, we take immense pride in our commitment to providing cutting-edge tools that empower researchers worldwide. For nearly two decades, our Compresstome Vibratome has been a trusted resource in the scientific community. We are thrilled to highlight a recent peer-reviewed publication that underscores the exceptional capabilities of our Compresstome.

Comparison of Compresstome & Other Vibratome

Here, we want to shine a spotlight on a notable publication by Abdelaal and colleagues. Although this research was published back in 2015 in the journal Biological Procedures Online, its findings continue to resonate within the scientific community.

In their groundbreaking study, Abdelaal et al. embarked on a systematic exploration of tissue sectioning techniques, comparing the well-established Vibratome with the innovative Compresstome. The primary objective was to evaluate the performance of these instruments across a spectrum of critical parameters, including cutting speed, chilling capabilities, specimen stabilization, section size, and the quality of subsequent section/staining. Here is the authors’ setup for comparing fresh tissue sectioning using a Compresstome and a Vibratome:

What emerged from this comprehensive study was a resounding endorsement of the Compresstome Vibratome. Researchers found it to be a superior choice on multiple fronts.

Key Findings on Better Compresstome Quality

The study’s findings provide compelling evidence of the superior performance of the Compresstome Vibratome:

1. Speed and Efficiency: The Compresstome outpaced the other market Leica Vibratome, producing sections approximately 5 times faster. This efficiency is a game-changer for researchers who require quick and precise tissue sectioning.

2. Ease of Use: Cutting fresh tissue sections with the Compresstome was found to be more straightforward, simplifying the process and enhancing productivity.

3. Section Size: Researchers using the Compresstome can create larger tissue sections, expanding possibilities for experimentation and analysis.

4. Consistent Quality: Immunofluorescent staining of sections obtained from both instruments yielded equivalent results, confirming the Compresstome’s ability to maintain high-quality standards.

Here is a captivating confocal image showcasing fresh lymphoid tissue sections from this publication. On the left, you see sections cut with the Compresstome vibratome, while the right features sections cut with the traditional Vibratome. This image vividly highlights the intricate cellular composition within these tissues, making it a testament to the precision and efficiency of the Compresstome vibratome.

Compresstome Vibratome for Immunohistochemistry Sections

The publication’s conclusion leaves no room for doubt: the Compresstome Vibratome stands as the superior choice for generating fresh, unfixed primate tissue sections and for making tissue sections for immunohistochemistry. Its enhanced efficiency, ease of use, and ability to produce larger sections make it an invaluable tool for researchers in various fields.

At Precisionary Instruments, we are honored to have supported academic researchers worldwide for nearly two decades, and this peer-reviewed publication further solidifies the strengths of our Compresstome Vibratome. We remain dedicated to providing cutting-edge solutions that empower scientists to push the boundaries of research and discovery. To learn more about this remarkable study, please read the full publication.

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