Upcoming Webinar | December 9 | Mouse Organotypic Brain Slices…

COMPRESSTOME® VF-800-0Z

Large Diameter Vibrating Microtome

Our Compresstome® VF-800-0Z tissue slicer is a fully-automated large diameter vibrating microtome capable of embedding large organs or multiple samples simultaneously for preclinical uses. Experimental applications include:

  • High-throughput tissue sectioning
  • Slice cultures for drug screening
  • Large diameter samples (i.e., primate brain)

Key Features of the VF-800-0Z Vibratome

Key Features of the VF-800-0Z Vibratome

User-friendly controls: Fully integrated control box has intuitive control parameters for controlling tissue sectioning

Compact Design: Small design for a vibratome that can section large tissues

Ultra precision: custom made blades for ultra precision of large tissues

Large cutting area: Can section samples up to 100 mm, or multiple samples

Durable: Equipped with a powerful, cordless motor for quiet and durable operation

The VF-800-0Z Excels Where Legacy Vibratomes Fall Short

At Precisionary, we know what gets in the way of your science. That’s why we offer industry-leading, reliable workhorse vibratomes backed by responsive expert support.

Healthy tissue sections from large organs

In a legacy vibratome, tissues are not well supported when slicing, causing the sample to be pushed and squished, which can lead to damaged cells and altered tissue architecture. The VF-800-0Z excels at slicing large, delicate specimens, such as whole brains from monkeys or human organs like the heart and liver, making it ideal for your large organ research.

Make hundreds of tissue sections fast

Designed to section many tissues at once, this vibratome enables precise sectioning for drug screening studies, including liver and kidney slices critical for metabolism and toxicity testing.

Full Automation for Consistent and Reliable Performance

The VF-800-0Z ensures reproducible tissue sections across a wide range of applications, delivering consistent results for long-term studies and diverse experimental needs.

VF-800-0Z Technical Specifications

Advance speed

0-5 mm/s, adjustable

Return speed

10 mm/s, fixed

Vibration frequency

0-60 Hz, adjustable

Vibration amplitude

1 mm, fixed

Z-Axis vibration

<4 µm

Compatible cutting blades

Tungsten carbide blades

Cutting angle

20 degrees, fixed

Thickness adjustment

Automatic, digital

Micrometer resolution

1 µm

Maximum tissue diameter

Maximum tissue length

85 mm

Slice thickness range

40 µm to 2000 µm

Cutting modes

Single or continuous, selectable

Buffer tray size (L x W x H)

330 x 153 x 25 mm

Power source

AC 100-110V, 200-240V
Only the original power supply unit (power cord) should be used with the Compresstome® VF-800-0Z model.

Power consumption

18 W

Dimensions (L x W x H)

350 x 368 x 415 mm

Weight

17.6 kg

Key Application Areas

Product Feature

Have More Questions?

Let’s Talk.

Researchers Trust Precisionary

Dr. Charlotte Dean

Imperial College London

We have used Compresstome tissue slicers for a number of years to generate lung slices (PCLS). Customer service has always been excellent and the team are very responsive. We have recently begun using the VF-510-0Z machine and it is generating high quality PCLS.

Dr. Hanan Osman-Ponchet

University of Burgundy

The Compresstome® VF-300-0Z has been an indispensable tool in our PKDERM lab for preparing high-quality human precision-cut lung slices (hPCLS).

Its versatility and rapid sectioning capabilities have enabled us to efficiently generate these valuable samples for our lung research studies. We have consistently achieved excellent section thickness and quality, allowing us to conduct detailed analyses of lung physiology and pathology and to obtain reliable results from our experiments.

The exceptional customer service from Precisionary Instruments has further enhanced our experience. Their prompt and knowledgeable support has been instrumental in ensuring the optimal performance of our Compresstome®.

Dr. Susanne Schmid

University of Western Ontario

We use brainstem slices of rats, which are particularly delicate and difficult to obtain. We were surprised by the performance of the vibratome, as it produces healthy brain slices comparable to much more expensive vibratomes. I also like the simplicity of the design of the vibratome.

FAQs

What is the maximum specimen diameter that the VF-800-0Z can accommodate?

The VF-800-0Z can accommodate specimens up to 100 mm in diameter, making it suitable for sectioning large organs or multiple samples simultaneously for high throughput.

What is the thinnest slice thickness achievable with the VF-800-0Z?

The VF-800-0Z is capable of producing tissue slices as thin as 40 microns, allowing for detailed histological analysis.

What are the key applications of the VF-800-0Z?

The VF-800-0Z is ideal for high-throughput tissue sectioning, slice cultures for drug screening,sectioning large diameter samples such as primate brains, and more.

Is the VF-800-0Z fully automated?

Yes, the VF-800-0Z is a fully automated vibrating microtome, allowing for precise and consistent sectioning with user-friendly controls. The control box is built into the machine, making it easier to place in a compact space without the need for an external control box.

Have More Questions?

Let’s Talk.

Custom Vibratome Options for the VF-800-0Z

Why Customize Your Vibratome?

Every research application has distinct sectioning demands. A custom vibratome allows you to achieve the best performance for your specimen size, throughput requirements, and lab setup.

Examples of customization needs include:

  1. Large or unique specimen sizes: e.g., entire human brain hemispheres for anatomical and connectomics studies.
  2. High-throughput workflows: for drug discovery and multi-organ screening assays that require rapid, reproducible sectioning.
  3. Specialized lab environments: such as biosafety cabinetsfume hoods, or automated systems where standard instrument dimensions may not fit.

Each of these situations benefits from a tailored vibratome that ensures precision, safety, and efficiency.

What Can Be Customized on Your VF-800-0Z Vibratome

Our engineering and applications teams work together to modify the VF-800-0Z large-diameter vibratome to your specific research needs.

Customizable features include:

  1. Specimen tube diameter: Adjustable for small, large, or oversized tissue samples during embedding.
  2. Instrument height and footprint: Optimized for use within fume hoods or limited-clearance workspaces.
  3. Cutting speed and vibration frequency: Tunable through customized electronic control systems.
  4. Additional integration options: Specialized cooling systems, automation compatibility, and imaging alignment.

How to Request a Custom Vibratome

Precisionary Instruments provides full support for custom vibratome design and manufacturing.

Our process includes:

  1. Consultation: Discuss your research goals, specimen types, and laboratory setup.
  2. Design & Budgeting: Our team proposes detailed specifications and cost estimates.
  3. Production & Testing: Each customized VF-800-0Z is engineered and validated for performance and safety.

Contact us today to start designing your custom vibratome

Request a

Quote

Take the first step to better tissue sectioning. Fill out the form to request a quote from Precisionary Instruments. We’ll respond within one business day.