Upcoming Webinar | July 8 | Precision Cut Liver Slice from Healthy and Diseased Human Liver Tissue
Advancing Neuroscience Through Live Imaging of the Brain’s Extracellular Space We are honored to spotlight the work of Dr. Virginia Puente, an MSCA and María Zambrano researcher at the University of the Basque Country (UPV/EHU). A pharmacist by training, Dr. Puente leads an ambitious and innovative research program centered on understanding how the extracellular space […]
Integrating the Compresstome® Vibrating Microtome into the Agilent Seahorse XF Flex Tissue Workflow ASHLAND, Mass., June 3, 2025 — Precisionary Instruments today announced a strategic partnership with Agilent to enhance the preparation of live tissue slices for use with the Agilent Seahorse XF Flex Analyzer and 3D Capture Microplate. This collaboration integrates Precisionary’s Compresstome® VF-510-0Z […]
The Growing Role of Organoids in Research Organoids are transforming biomedical research. These three-dimensional, multicellular models mimic the architecture and function of real human tissues, making them invaluable for studying complex processes such as organ development, cancer progression, and regenerative therapies. Derived from stem cells or primary tissues, organoids maintain the spatial organization, cellular diversity, […]
Featuring work by Heidi Kreckel, Ph.D. Candidate, Colorado State University Plant biologists have long faced a difficult challenge: how do you image live plant tissues in a way that maintains their cellular architecture, viability, and optical clarity? A recent paper by Heidi D. Kreckel and colleagues in Plant Cell, Tissue and Organ Culture answers this […]
Explore our detailed manual for mastering PCLS in respiratory research We’re thrilled to announce the launch of our comprehensive Precision-Cut Lung Slices Protocol Manual—a practical, researcher-friendly guide designed to help you get consistent, healthy lung tissue slices every time. Whether you’re just getting started with PCLS or are looking for ways to refine your technique, this […]
At Precisionary Instruments, we understand that preparing acute brain slices for electrophysiology is a highly technical and delicate process. Many researchers have reached out to us, looking for a clear and structured protocol that walks them through every step. In response, we have developed a detailed, step-by-step experimental guide, one of the first of its […]
At Precisionary Instruments, our team is the backbone of innovation in tissue sectioning technology. In this employee spotlight, we introduce Alyssa MacDonald, one of our talented Engineering Technicians, who plays a crucial role in ensuring the quality and precision of our vibratomes. A Hands-On Path to Engineering Alyssa’s journey into engineering is unique. With a […]
At Precisionary Instruments, our mission is to provide cutting-edge tissue sectioning solutions for researchers around the world. Behind every high-performance vibratome, microtome, and cryostat is a team of dedicated engineers who work tirelessly to ensure precision, durability, and usability. Today, we’re excited to spotlight Sam Moss, an engineer whose expertise and problem-solving skills help drive […]
Advancing skin research depends on high-quality tissue samples, and a recent study (Ziolkowski et al. from Science Advances) is a great example of how innovative sectioning techniques can make a big difference. This team of researchers set out to better understand touch detection in skin tissue, and to do that, they needed clear, precise sections […]
Microtome, vibratome, vibrating microtome…you’ve heard so many different terms for this type of laboratory equipment. Let us help you clear up any confusions in terminology! Defining microtome vs vibratome A microtome is a device used to cut very thin slices of tissue, called sections, for examination under a microscope. It typically uses a sharp, stationary […]
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