Tag: Tissue Sectioning

Meet the Team: Engineering Excellence with Sam Moss at Precisionary Instruments

At Precisionary Instruments, our mission is to provide cutting-edge tissue sectioning solutions for researchers around the world. Behind every high-performance vibratome, microtome, and cryostat is a team of dedicated engineers who work tirelessly to ensure precision, durability, and usability. Today, we’re excited to spotlight Sam Moss, an engineer whose expertise and problem-solving skills help drive […]

Written by on March 24, 2025

Understanding Immunohistochemistry Tools: Comparing Vibratomes, Rotary Microtomes, and Cryostats

Hi there! As Chief Scientific Officer at Precisionary Instruments, I’ve had the privilege of working with countless researchers to optimize their tissue sectioning for immunohistochemistry (IHC). Whether you’re studying protein localization, cellular structures, or disease markers, the quality of your tissue sections can make or break your experiment. One of the most common questions I […]

Written by on December 17, 2024

Advances in Tissue Sectioning: Transitioning from Sliding Microtomes to Modern Vibratomes and Cryostats

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the importance of ACSF, its composition, and practical tips to optimize its use.

Written by on October 31, 2024

Can I (and How Do I) Use Frozen Tissue to Be Cut on a Vibratome?

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the importance of ACSF, its composition, and practical tips to optimize its use.

Written by on October 31, 2024