Category: Experimental Solutions
The Growing Role of Organoids in Research Organoids are transforming biomedical research. These three-dimensional, multicellular models mimic the architecture and function of real human tissues, making them invaluable for studying complex processes such as organ development, cancer progression, and regenerative therapies. Derived from stem cells or primary tissues, organoids maintain the spatial organization, cellular diversity, […]
Written by Abby Chu on June 3, 2025
Explore our detailed manual for mastering PCLS in respiratory research We’re thrilled to announce the launch of our comprehensive Precision-Cut Lung Slices Protocol Manual—a practical, researcher-friendly guide designed to help you get consistent, healthy lung tissue slices every time. Whether you’re just getting started with PCLS or are looking for ways to refine your technique, this […]
Written by Abby Chu on April 25, 2025
At Precisionary Instruments, because so many of our tissue slicer users handle fixed tissue, we often get asked about antigen retrieval. Today, we’d like to cover this as a short explanatory topic! What is antigen retrieval and why is it important? Have you ever worked with fixed tissue? If you process tissue slices for immunological […]
Written by Abby Chu on March 31, 2025
At Precisionary Instruments, we understand that preparing acute brain slices for electrophysiology is a highly technical and delicate process. Many researchers have reached out to us, looking for a clear and structured protocol that walks them through every step. In response, we have developed a detailed, step-by-step experimental guide, one of the first of its […]
Written by Abby Chu on March 26, 2025
Are you struggling to keep your specimen tube secure? Do you need a dependable solution for sample embedding? Wish you had a “third hand” to help? If you’ve ever faced the challenge of keeping your specimen tube steady while embedding tissue, we have the perfect solution. Introducing the SteadyHold Tube Stabilizer—Precisionary Instruments’ latest innovation designed […]
Written by Abby Chu on March 7, 2025
Starting the year with fresh research goals? If improving your tissue sectioning workflow is a priority, our 30-day demo program for the Compresstome VF-510-0Z is the perfect opportunity to explore a vibratome that sections tissue faster, preserves sample integrity, and simplifies your lab work. We understand that some institutions require a demo before purchasing, and […]
Written by Abby Chu on February 28, 2025
Acute brain slices are a cornerstone of neurophysiological research, providing an essential platform for investigating neuronal activity through techniques like patch-clamp electrophysiology. The preparation of these delicate tissue slices requires precision, care, and specialized tools to preserve their viability and functionality. Understanding the challenges neurophysiologists face, we are excited to introduce the Compresstome Vibratome Electrophysiology […]
Written by Abby Chu on February 21, 2025
Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the […]
Written by Abby Chu on September 10, 2024
In the realm of scientific research, particularly in histology, neuroscience, and pathology, precise sectioning of biological samples is critical. Two primary instruments used for this purpose are vibratomes and microtomes. Each has its unique advantages and applications, as well as some overlapping uses. In this article, we will explore the different experimental applications for vibratomes […]
Written by Abby Chu on July 22, 2024
Have you ever wanted to make one cut and get enough tissue slices for an entire 24-well plate? Well, our new Compresstome VF-800-0Z is now capable of doing that! For instance, just ONE tissue section can yield 20-30 or more samples, and can fill an entire 24-well plate for your experiments. What is High-Throughput Tissue […]
Written by Abby Chu on June 12, 2024
