The field of histology and tissue sectioning has seen remarkable advancements over the years, and one essential tool that has played a significant role in this progress is the rotary microtome. Rotary microtomes have revolutionized sectioning techniques, allowing researchers to obtain thin and precise tissue sections for various applications. In this article, we will delve […]

Patch-clamp electrophysiology is a powerful technique used by neurophysiologists to investigate the electrical properties of neurons. Central to this process is the preparation of acute brain slices, which requires specialized tools and precise handling to maintain slice health. In this article, we will explore the essential tools for patch-clamp electrophysiology, with a particular focus on […]

Oxygenation of a buffer solution for electrophysiology is important to maintain the viability of cells and tissues, as well as to prevent the formation of artifacts during recordings. Here are the general steps to oxygenate a buffer solution for electrophysiology: Prepare the buffer solution according to the protocol for your specific experiment. Fill a clean […]

When it comes to studying large-sized organs or tissues, such as brains, kidneys, or even entire embryos, researchers often face a significant challenge in obtaining thin and consistent sections for analysis. Traditional sectioning methods may struggle to handle the size and delicate nature of these specimens. However, we at Precisionary Instruments have developed a powerful […]

Electrophysiology is the study of the electrical properties of biological cells and tissues, and how these properties generate and propagate electrical signals in the body. This field is used to understand the electrical activity of cells in the heart, brain, and other organs, and to diagnose and treat various health conditions, such as arrhythmias and […]

How do I embed and cut great spinal cord slice? You asked, and we listened! We realized that embedding spinal cord tissue for cutting slices is quite difficult. Working with our biomedical illustrator, we came up with this visual protocol to help you embed spinal cord for cutting: How about some spinal cord references? You got it! […]

Honoring Women in Neurophysiology Welcome to March 2021! This month is Women’s History Month, and March 8 is International Women’s Day. We would like to share the stories and impact of 4 female neuroscientists from around the world. These individuals completed neurophysiology research that have greatly advanced our understanding of how neurons communicate with each other. By using […]