Category: Experimental Solutions

Enhancing Neurophysiological Research with the Vibratome Electrophysiology Kit for Acute Brain Slices [UPDATED]

Acute brain slices are a cornerstone of neurophysiological research, providing an essential platform for investigating neuronal activity through techniques like patch-clamp electrophysiology. The preparation of these delicate tissue slices requires precision, care, and specialized tools to preserve their viability and functionality. Understanding the challenges neurophysiologists face, we are excited to introduce the Compresstome Vibratome Electrophysiology […]

Written by on February 21, 2025

Understanding ACSF: A Crucial Solution for Electrophysiology and Acute Brain Slice Maintenance

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during sensitive experiments like patch-clamp recordings. In this article, we will […]

Written by on September 10, 2024

Understanding the Different Experimental Applications for Vibratomes vs. Microtomes (vs. Both)

In the realm of scientific research—particularly in histology, neuroscience, and pathology—the precise sectioning of biological samples is critical. Two primary instruments used for this purpose are vibratomes and microtomes. Each has its unique advantages and specific applications, as well as some overlapping uses. In this article, we will explore the different experimental applications for vibratomes […]

Written by on July 22, 2024

Vibratome for High-Throughput Tissue Sectioning

Vibratome for High-Throughput Tissue Sectioning Have you ever wanted to make one cut and get enough tissue slices for an entire 24-well plate? Well, our new Compresstome® VF-800-0Z is now capable of doing exactly that! For instance, just ONE tissue section can yield 20 to 30 or more samples, easily filling an entire 24-well plate […]

Written by on June 12, 2024

Compresstome Vibrating Microtome Empowers Cutting-Edge Neuroscience Research at University Hospital Würzburg

Leading the charge in innovative neuroscience research is Prof. Carsten Hagemann, heading the Section Experimental Neurosurgery within the Neurosurgery Department at the University Hospital Würzburg, Germany. With a firm commitment to bridging the gap between laboratory discoveries and clinical applications, this section stands at the forefront of translational neuroscience research. Interdisciplinary Collaboration in Section Experimental […]

Written by on May 16, 2024

Exploring Neuropsychiatric Conditions: A Lab Spotlight on Dr. Jordan Logue’s Research at MUSC Using Compresstome Vibratome

Meet the McMahon Research Group In the bustling corridors of the Medical University of South Carolina’s Basic Science Building resides a dynamic research group led by Vice President of Research Dr. Lori McMahon. Among her dedicated team is postdoctoral researcher Dr. Jordan Logue, whose work delves into the intricate realm of neuropsychiatric conditions, particularly focusing […]

Written by on April 2, 2024

Lab Spotlight: Dr. Gregg Wildenberg’s Lab Unravels Neuroanatomy Mysteries with Precisionary Instruments

Wildenberg Lab Supported by Precisionary Instruments In our latest Lab Spotlight, we’re thrilled to feature the groundbreaking work of Dr. Gregg Wildenberg and his team at The University of Chicago. Dr. Wildenberg also holds a joint appointment at Argonne National Laboratory. Dr. Wildenberg’s lab, composed of a dynamic team of eight individuals, is dedicated to […]

Written by on April 2, 2024

Precisionary Compresstome Vibratome Lab Spotlight: Henderson Lab at Marshall University

Welcome to another edition of our Lab Spotlight series, where we delve into the innovative research happening in labs around the world that utilize Precisionary Instruments’ Compresstome vibratome. Today, we’re excited to shine the spotlight on Associate Professor Brandon Henderson’s research lab, located at the Joan C. Edwards School of Medicine at Marshall University. About […]

Written by on April 2, 2024

Precisionary Instruments Celebrates Brain Awareness Week 2024: Advancing Neuroscience Together

What is Brain Awareness Week 2024? Brain Awareness Week (BAW) is an annual global initiative organized by the Dana Foundation, dedicated to raising public awareness about the progress and importance of brain research. It serves as a platform to highlight advancements in the understanding, diagnosis, treatment, and prevention of brain-related disorders such as Alzheimer’s, Parkinson’s, stroke, […]

Written by on February 26, 2024

Experimental Solutions: Choosing the Right Tissue Slicer for Your Research

Choosing the Right Tissue Slicer Are you struggling to determine whether a vibratome, microtome, or cryostat is the best fit for your tissue sectioning needs? You’re not alone. Many scientists grapple with this decision when embarking on experimental projects involving tissue samples. To simplify this process, we’ve crafted a series of visual decision flowcharts to […]

Written by on February 15, 2024