Tag: blog

Understanding ACSF: A Crucial Solution for Electrophysiology and Acute Brain Slice Maintenance

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the […]

Written by on September 10, 2024

Understanding the Different Experimental Applications for Vibratomes vs. Microtomes (vs. Both)

In the realm of scientific research, particularly in histology, neuroscience, and pathology, precise sectioning of biological samples is critical. Two primary instruments used for this purpose are vibratomes and microtomes. Each has its unique advantages and applications, as well as some overlapping uses. In this article, we will explore the different experimental applications for vibratomes […]

Written by on July 22, 2024

Vibrating Microtome and Vibratome: Understanding Similarities and Differences

If you’re involved in tissue sectioning, you’ve probably heard the terms “vibrating microtome” and “vibratome” thrown around quite a bit. Spoiler alert: they’re actually the same thing! But let’s dive a bit deeper into what these nifty tools are, their history, and how Precisionary Instruments has made some game-changing improvements over the years with our […]

Written by on July 22, 2024

Vibratome for High-Throughput Tissue Sectioning

Have you ever wanted to make one cut and get enough tissue slices for an entire 24-well plate? Well, our new Compresstome VF-800-0Z is now capable of doing that! For instance, just ONE tissue section can yield 20-30 or more samples, and can fill an entire 24-well plate for your experiments. Check this out:   […]

Written by on June 12, 2024

Lab Spotlight: Dr. Lingyan Shi and the Laboratory of Optical Bioimaging and Spectroscopy at UC San Diego

Visualizing Metabolic Changes in Aging and Diseases “Our goal is to develop and apply new ultrafast laser scanning multimodal imaging and spectroscopic technologies, such as stimulated Raman scattering (SRS), second harmonic generation (SHG), and multiphoton fluorescence (MPF) microscopy, for visualizing molecular composition and metabolic dynamics in situ at subcellular resolution to study aging and diseases,” […]

Written by on June 5, 2024

Compresstome Vibrating Microtome Empowers Cutting-Edge Neuroscience Research at University Hospital Würzburg

Leading the charge in innovative neuroscience research is Prof. Carsten Hagemann, heading the Section Experimental Neurosurgery within the Neurosurgery Department at the University Hospital Würzburg, Germany. With a firm commitment to bridging the gap between laboratory discoveries and clinical applications, this section stands at the forefront of translational neuroscience research. Interdisciplinary Collaboration in Section Experimental […]

Written by on May 16, 2024

Exploring Neuropsychiatric Conditions: A Lab Spotlight on Dr. Jordan Logue’s Research at MUSC Using Compresstome Vibratome

Meet the McMahon Research Group In the bustling corridors of the Medical University of South Carolina’s Basic Science Building resides a dynamic research group led by Vice President of Research Dr. Lori McMahon. Among her dedicated team is postdoctoral researcher Dr. Jordan Logue, whose work delves into the intricate realm of neuropsychiatric conditions, particularly focusing […]

Written by on April 2, 2024

Lab Spotlight: Dr. Gregg Wildenberg’s Lab Unravels Neuroanatomy Mysteries with Precisionary Instruments

Wildenberg Lab Supported by Precisionary Instruments In our latest Lab Spotlight, we’re thrilled to feature the groundbreaking work of Dr. Gregg Wildenberg and his team at The University of Chicago. Dr. Wildenberg also holds a joint appointment at Argonne National Laboratory. Dr. Wildenberg’s lab, composed of a dynamic team of eight individuals, is dedicated to […]

Written by on April 2, 2024

Precisionary Compresstome Vibratome Lab Spotlight: Henderson Lab at Marshall University

Welcome to another edition of our Lab Spotlight series, where we delve into the innovative research happening in labs around the world that utilize Precisionary Instruments’ Compresstome vibratome. Today, we’re excited to shine the spotlight on Associate Professor Brandon Henderson’s research lab, located at the Joan C. Edwards School of Medicine at Marshall University. About […]

Written by on April 2, 2024

Precisionary Instruments Celebrates Brain Awareness Week 2024: Advancing Neuroscience Together

What is Brain Awareness Week 2024? Brain Awareness Week (BAW) is an annual global initiative organized by the Dana Foundation, dedicated to raising public awareness about the progress and importance of brain research. It serves as a platform to highlight advancements in the understanding, diagnosis, treatment, and prevention of brain-related disorders such as Alzheimer’s, Parkinson’s, stroke, […]

Written by on February 26, 2024