Upcoming Webinar | May 13 | Organotypic Tumor Slices: A Platform for Identifying Therapeutic Targets in Cancer-Stroma Interactions
At Precisionary Instruments, our mission is to provide cutting-edge tissue sectioning solutions for researchers around the world. Behind every high-performance vibratome, microtome, and cryostat is a team of dedicated engineers who work tirelessly to ensure precision, durability, and usability. Today, we’re excited to spotlight Sam Moss, an engineer whose expertise and problem-solving skills help drive […]
Advancing skin research depends on high-quality tissue samples, and a recent study (Ziolkowski et al. from Science Advances) is a great example of how innovative sectioning techniques can make a big difference. This team of researchers set out to better understand touch detection in skin tissue, and to do that, they needed clear, precise sections […]
Acute brain slices are a cornerstone of neurophysiological research, providing an essential platform for investigating neuronal activity through techniques like patch-clamp electrophysiology. The preparation of these delicate tissue slices requires precision, care, and specialized tools to preserve their viability and functionality. Understanding the challenges neurophysiologists face, we are excited to introduce the Compresstome Vibratome Electrophysiology […]
Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the […]
In the realm of scientific research, particularly in histology, neuroscience, and pathology, precise sectioning of biological samples is critical. Two primary instruments used for this purpose are vibratomes and microtomes. Each has its unique advantages and applications, as well as some overlapping uses. In this article, we will explore the different experimental applications for vibratomes […]
If you’re involved in tissue sectioning, you’ve probably heard the terms “vibrating microtome” and “vibratome” thrown around quite a bit. Spoiler alert: they’re actually the same thing! But let’s dive a bit deeper into what these nifty tools are, their history, and how Precisionary Instruments has made some game-changing improvements over the years with our […]
Have you ever wanted to make one cut and get enough tissue slices for an entire 24-well plate? Well, our new Compresstome VF-800-0Z is now capable of doing that! For instance, just ONE tissue section can yield 20-30 or more samples, and can fill an entire 24-well plate for your experiments. What is High-Throughput Tissue […]
Visualizing Metabolic Changes in Aging and Diseases “Our goal is to develop and apply new ultrafast laser scanning multimodal imaging and spectroscopic technologies, such as stimulated Raman scattering (SRS), second harmonic generation (SHG), and multiphoton fluorescence (MPF) microscopy, for visualizing molecular composition and metabolic dynamics in situ at subcellular resolution to study aging and diseases,” […]
Leading the charge in innovative neuroscience research is Prof. Carsten Hagemann, heading the Section Experimental Neurosurgery within the Neurosurgery Department at the University Hospital Würzburg, Germany. With a firm commitment to bridging the gap between laboratory discoveries and clinical applications, this section stands at the forefront of translational neuroscience research. Interdisciplinary Collaboration in Section Experimental […]
Meet the McMahon Research Group In the bustling corridors of the Medical University of South Carolina’s Basic Science Building resides a dynamic research group led by Vice President of Research Dr. Lori McMahon. Among her dedicated team is postdoctoral researcher Dr. Jordan Logue, whose work delves into the intricate realm of neuropsychiatric conditions, particularly focusing […]
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