Upcoming Webinar | October 27 | A Multi-Scale Neuroscience Approach to CNS Therapeutic Target Discovery
At Precisionary Instruments, we understand that preparing acute brain slices for electrophysiology is a highly technical and delicate process. Many researchers have reached out to us, looking for a clear and structured protocol that walks them through every step. In response, we have developed a detailed, step-by-step experimental guide, one of the first of its […]
Starting the year with fresh research goals? If improving your tissue sectioning workflow is a priority, our 30-day demo program for the Compresstome VF-510-0Z is the perfect opportunity to explore a vibratome that sections tissue faster, preserves sample integrity, and simplifies your lab work. We understand that some institutions require a demo before purchasing, and […]
Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during sensitive experiments like patch-clamp recordings. In this article, we will […]
In the realm of scientific research (particularly in histology, neuroscience, and pathology), the precise sectioning of biological samples is critical. Two primary instruments used for this purpose are vibratomes and microtomes. Each has its unique advantages and specific applications, as well as some overlapping uses. In this article, we will explore the different experimental applications […]
Oxygenation of a buffer solution for electrophysiology is important to maintain the viability of cells and tissues, as well as to prevent the formation of artifacts during recordings. Here are the general steps to oxygenate a buffer solution for electrophysiology: Prepare the buffer solution according to the protocol for your specific experiment. Fill a clean […]
Electrophysiology is the study of the electrical properties of biological cells and tissues, and how these properties generate and propagate electrical signals in the body. This field is used to understand the electrical activity of cells in the heart, brain, and other organs, and to diagnose and treat various health conditions, such as arrhythmias and […]
