Category: Uncategorized

What is the Difference Between On-Slide Staining vs. Free-Floating Staining?

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the importance of ACSF, its composition, and practical tips to optimize its use.

Written by on October 31, 2024

Advances in Tissue Sectioning: Transitioning from Sliding Microtomes to Modern Vibratomes and Cryostats

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the importance of ACSF, its composition, and practical tips to optimize its use.

Written by on October 31, 2024

Can I (and How Do I) Use Frozen Tissue to Be Cut on a Vibratome?

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during experiments like patch-clamp recordings. In this article, we’ll explore the importance of ACSF, its composition, and practical tips to optimize its use.

Written by on October 31, 2024

Exploring the World of Cardiac Tissue Slicing

Getting Started with Cardiac Slicing Welcome, fellow scientists, to a journey into the fascinating realm of cardiac tissue slicing! In the spirit of Valentine’s Day, where hearts take center stage as symbols of love and affection, let’s explore the intricate world of cardiac tissue and how precision slicing can unveil its mysteries. The History of Cardiac Slicing Our journey […]

Written by on January 29, 2024

Mapping the Projectome Using Compresstome Vibratome

The human brain, a complex network of billions of neurons, remains one of the greatest enigmas of science. In the quest to decode its mysteries, scientists have embarked on an ambitious endeavor called “projectomes.” Projectomes are comprehensive maps of the brain that detail the trajectories of individual long-distance projecting neurons, shedding light on how different […]

Written by on January 5, 2024

What is Compresstome Auto Zero-Z Technology?

Compresstome Auto Zero-Z® Patented Technology The Compresstome® vibrating microtome lineup incorporates a significant technological advancement: our patented Auto Zero-Z® technology. This innovative feature is integral to Compresstome® models with names ending in “-0Z,” as it ensures meticulous alignment, eliminating oscillating deviations along the z-axis throughout the cutting process (Figure 1). Figure 1. Auto Zero-Z technology is equivalent to […]

Written by on January 3, 2024

Precisionary Instruments at ACG 2023 in Vancouver

Explore our Vibratomes and Microtomes for Precision-Cut Tissue Slices Precisionary Instruments is thrilled to announce our participation in the upcoming American College of Gastroenterology (ACG) conference in Vancouver, BC, Canada. We invite you to visit our booth #1231 from October 22-24, 2023, where you can explore our cutting-edge vibratomes and microtomes that are specifically designed […]

Written by on August 14, 2023

Precisionary Instruments Will Be at the 2023 NSH Convention

    Join Precisionary Instruments at Booth #1418 – Explore Our Vibratomes and Microtomes at NSH 2023 Precisionary Instruments is thrilled to announce our participation at the upcoming 2023 National Society of Histotechnology (NSH) Conference, taking place from September 8-12, 2023 in Baltimore, MD. We invite you to visit us at Booth #1418, where we […]

Written by on July 24, 2023

Precisionary Celebrates World Brain Day 2023!

Welcome to World Brain Day 2023, a global initiative dedicated to raising awareness about brain health and neurological disorders. This happens each year on July 22! On this day, we come together to promote understanding, support those affected by brain-related conditions, and foster collaboration among researchers, healthcare professionals, and communities. Join us in our mission […]

Written by on June 26, 2023

Customer Testimonials at Precisionary Instruments

At Precisionary Instruments, we have almost two decades of customer service experience and microtome expertise. We have strategically built our brand to be trusted in many research and clinical areas, including electrophysiology, immunohistochemistry, precision-cut tissue, and organotypic culture slicing. Now, hear it directly from our customers!   We believe in the quality of our products […]

Written by on June 5, 2023