Upcoming Webinar | August 4 | Using Surgically Resected Brain Tissue to Study the Physiological Maturation of Human Neurons
How complex human cognition arises from neurons exchanging electrical impulses is one of the great questions in neuroscience and one to which I have dedicated my scientific career. During my doctoral training, I had the exciting opportunity to directly interrogate the electrical properties of live human brain cells in tissue recovered from neurosurgical procedures, revealing […]
Sampada Tamhankar is a PhD candidate in the Department of Drug Discovery and Development at Auburn University, where she conducts her research in Dr. Rajesh Amin’s laboratory. Dr. Amin’s group focuses on developing novel small-molecule therapeutics for neurodegenerative diseases—including Alzheimer’s disease and frontotemporal dementia (FTD). Sampada’s work centers on understanding remyelination mechanisms in FTD using […]
Dr. Jian-young Wu is a Professor of Neuroscience at Georgetown University Medical Center, where he has led a research lab since 1995. He completed his PhD at Peking University in 1986, followed by postdoctoral training at Yale University from 1986 to 1993. Dr. Wu’s laboratory focuses on studying population neuronal activity—large-scale, coordinated firing patterns that […]
Dr. Virginia Puente is a neuroscientist whose work focuses on how the structure and dynamics of the brain’s extracellular space (ECS) modulate neuronal signaling. Her research integrates advanced tools including optogenetics, fluorescence imaging, and super-resolution techniques like STED microscopy and SUSHI (Super-resolution Shadow Imaging) to examine neuronal excitability and synaptic plasticity.
Researchers have used the Compresstome® in their procedure to section mouse embryo hypothalamus that has been injected with DNA and electroporated. This procedure demonstrates how it is possible to transfect nuclei in the hypothalamus region which are less accessible than those in superficial regions. Following this procedure additional experiments can be performed such as immunohistochemistry and in situ hybridization.
Often heralded as leaders in the field, the Allen Brain institute performs pioneering research on all manner of brain tissue. Working with brain tissue can often be as frustrating as it is rewarding. Slicing brain tissue presents many challenges. The tissue is a combination of soft and fibrous regions. For over a decade, researchers at […]
Dr. Junshi Wang is an enthusiastic neuroscientist who has been investigating neural mechanisms underlying drug addiction for…
Dr. Henderson is an Assistant Professor in the Department of Biomedical Sciences at Marshall University’s Joan C. Edwards…
Jonathan T. Ting is an Assistant Investigator at the Allen Institute, where he joined in 2013 to provide electrophysiology…
