Getting Started with Cardiac Slicing Welcome, fellow scientists, to a journey into the fascinating realm of cardiac tissue slicing! In the spirit of Valentine’s Day, where hearts take center stage as symbols of love and affection, let’s explore the intricate world of cardiac tissue and how precision slicing can unveil its mysteries. The History of Cardiac Slicing Our journey […]
The human brain, a complex network of billions of neurons, remains one of the greatest enigmas of science. In the quest to decode its mysteries, scientists have embarked on an ambitious endeavor called “projectomes.” Projectomes are comprehensive maps of the brain that detail the trajectories of individual long-distance projecting neurons, shedding light on how different […]
Compresstome Auto Zero-Z® Patented Technology The Compresstome® vibrating microtome lineup incorporates a significant technological advancement: our patented Auto Zero-Z® technology. This innovative feature is integral to Compresstome® models with names ending in “-0Z,” as it ensures meticulous alignment, eliminating oscillating deviations along the z-axis throughout the cutting process (Figure 1). Figure 1. Auto Zero-Z technology is equivalent to […]
Exciting Research Update from Stanford University’s Madison Lab!As the global community of Compresstome® vibratome users continues to expand, we are thrilled to spotlight the groundbreaking research of Professor Daniel Madison and his team at Stanford University. The Compresstome® Vibratome in the Madison Lab: The Madison Lab specializes in exploring the fundamental properties, plasticity, and modulation of […]
Dear Precisionary Customers, As the year comes to a close and we enter the holiday season, I wanted to take a moment to express my deepest gratitude to each and every one of you. Your unwavering support and trust in Precisionary Instruments have been instrumental in our continued success and growth. We are truly grateful […]
Using precision-cut lung slices (PCLS) as an experimental model has revolutionized the study of respiratory diseases. PCLS offer a unique platform to investigate disease mechanisms, explore cellular and molecular interactions, and evaluate potential therapeutic interventions. With their preserved tissue architecture, cellular diversity, and physiological relevance, PCLS enable researchers to dissect complex respiratory pathologies, such as […]
The concept of using tissue slices to study organ metabolism and disease emerged in the 1920s, marking a significant milestone in the field of biomedical research. Researchers recognized the immense value of preserving the structural integrity and functional properties of tissues by carefully slicing them into thin sections. This breakthrough technique allowed investigators to study […]
Respiratory diseases have a profound impact on human health, making their study of paramount importance. These diseases, including asthma, chronic obstructive pulmonary disease (COPD), and pulmonary infections, impose a significant burden on individuals and society as a whole. They can cause debilitating symptoms, reduce quality of life, and even lead to premature death. Moreover, respiratory […]
Frontotemporal dementia (FTD) is a type of dementia that affects the frontal and temporal lobes of the brain, which are responsible for personality, behavior, language, and emotional regulation. FTD is also sometimes referred to as frontotemporal lobar degeneration (FTLD) or Pick’s disease. FTD is caused by the degeneration of neurons in the frontal and temporal […]
Explore our Vibratomes and Microtomes for Precision-Cut Tissue Slices Precisionary Instruments is thrilled to announce our participation in the upcoming American College of Gastroenterology (ACG) conference in Vancouver, BC, Canada. We invite you to visit our booth #1231 from October 22-24, 2023, where you can explore our cutting-edge vibratomes and microtomes that are specifically designed […]
