Tag: compresstome

Lab Spotlight: Heidi Kreckel & the Levinger Lab – Visualizing Cryoprotectant Uptake in Plant Tissues

Introducing the Levinger Lab and PhD Candidate Heidi Kreckel At Colorado State University, the Levinger Lab—led by Professor Nancy E. Levinger—has long been a pioneer in exploring how molecules behave in nanoconfined environments. Recently, the Levinger group has added studies exploring how plant material can withstand cryoprotectant treatments that help it survive at ultralow temperatures.   […]

Written by on January 26, 2026

Lab Spotlight: Investigating Immune–Vascular Interactions in Lung Disease Using Precision-Cut Lung Slices

Figure 1. Joulia lab (June 2025)   Meet the Joulia Lab at the National Heart and Lung Institute Dr. Régis Joulia leads a newly established research group based at the National Heart and Lung Institute (NHLI) at Imperial College London. Supported by funding from the Wellcome Trust and other charitable organizations, the Joulia Lab focuses on […]

Written by on January 23, 2026

Why Researchers Are Choosing the Compresstome Over Cryostats

Simplify your tissue sectioning. Preserve integrity. Eliminate freezing artifacts. Traditional cryostats have long been the go-to tool for tissue sectioning, but they come with significant drawbacks—freezing damage, bulky design, and intensive maintenance. The Compresstome VF-510-0Z offers a modern alternative: a next-generation vibrating microtome that enables fast, reliable sectioning of live or fixed tissues—without the need […]

Written by on November 4, 2025

Precisionary Instruments Expands Global Reach with Launch of Precisionary Europe

Precisionary Europe Is Here to Support Our Researchers! We’re excited to share an important announcement: Precisionary Instruments now has an official European presence—Precisionary Europe! 🎉 For years, our Compresstome® vibratomes have been helping researchers around the world make breakthroughs in neuroscience, physiology, cancer biology, and many other fields. In Europe, our valued partners at Red […]

Written by on October 15, 2025

Lab Spotlight: Dr. Virginia Puente

Advancing Neuroscience Through Live Imaging of the Brain’s Extracellular Space We are honored to spotlight the work of Dr. Virginia Puente, an MSCA and María Zambrano researcher at the University of the Basque Country (UPV/EHU). A pharmacist by training, Dr. Puente leads an ambitious and innovative research program centered on understanding how the extracellular space […]

Written by on July 10, 2025

Precisionary Instruments Partners with Agilent to Advance Live Tissue Metabolic Analysis

Integrating the Compresstome® Vibrating Microtome into the Agilent Seahorse XF Flex Tissue Workflow ASHLAND, Mass., June 3, 2025 — Precisionary Instruments today announced a strategic partnership with Agilent to enhance the preparation of live tissue slices for use with the Agilent Seahorse XF Flex Analyzer and 3D Capture Microplate. This collaboration integrates Precisionary’s Compresstome® VF-510-0Z […]

Written by on June 3, 2025

Sectioning Organoids with Precision: How the Compresstome Enables Advanced 3D Tissue Research

The Growing Role of Organoids in Research Organoids are transforming biomedical research. These three-dimensional, multicellular models mimic the architecture and function of real human tissues, making them invaluable for studying complex processes such as organ development, cancer progression, and regenerative therapies. Derived from stem cells or primary tissues, organoids maintain the spatial organization, cellular diversity, […]

Written by on June 3, 2025

New Protocol Guide: Everything You Need to Know About Precision-Cut Lung Slices (PCLS)

Explore our detailed manual for mastering PCLS in respiratory research We’re thrilled to announce the launch of our comprehensive Precision-Cut Lung Slices Protocol Manual—a practical, researcher-friendly guide designed to help you get consistent, healthy lung tissue slices every time. Whether you’re just getting started with PCLS or are looking for ways to refine your technique, this […]

Written by on April 25, 2025

A Comprehensive Step-by-Step Guide to Acute Brain Slices for Electrophysiology

At Precisionary Instruments, we understand that preparing acute brain slices for electrophysiology is a highly technical and delicate process. Many researchers have reached out to us, looking for a clear and structured protocol that walks them through every step. In response, we have developed a detailed, step-by-step experimental guide, one of the first of its […]

Written by on March 26, 2025