Tag: acute brain slices

Precisionary Instruments Partners with Agilent to Advance Live Tissue Metabolic Analysis

Integrating the Compresstome® Vibrating Microtome into the Agilent Seahorse XF Flex Tissue Workflow ASHLAND, Mass., June 3, 2025 — Precisionary Instruments today announced a strategic partnership with Agilent to enhance the preparation of live tissue slices for use with the Agilent Seahorse XF Flex Analyzer and 3D Capture Microplate. This collaboration integrates Precisionary’s Compresstome® VF-510-0Z […]

Written by on June 3, 2025

A Comprehensive Step-by-Step Guide to Acute Brain Slices for Electrophysiology

At Precisionary Instruments, we understand that preparing acute brain slices for electrophysiology is a highly technical and delicate process. Many researchers have reached out to us, looking for a clear and structured protocol that walks them through every step. In response, we have developed a detailed, step-by-step experimental guide, one of the first of its […]

Written by on March 26, 2025

Understanding ACSF: A Crucial Solution for Electrophysiology and Acute Brain Slice Maintenance

Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during sensitive experiments like patch-clamp recordings. In this article, we will […]

Written by on September 10, 2024