Upcoming Webinar | April 14 | Mechanisms of Microglia-Mediated Neurodegeneration in Alzheimer’s Disease
At Precisionary Instruments, our engineering philosophy is built on a single premise: stability equals quality. This is why the Compresstome® is designed specifically to utilize agarose embedding for every tissue specimen. While traditional vibratomes often rely on a single point of adhesion to a flat stage, the Compresstome® is engineered to work with an agarose […]
In the world of precision tissue sectioning, the Compresstome® is a powerful engine, but the quality of the final slice often depends on the “fuel” and the “handling”—the environment in which a sample is sliced and the specialized tools used to manipulate it. Whether the goal is to maintain the firing of a neuron or […]
Simplify your tissue sectioning. Preserve integrity. Eliminate freezing artifacts. Traditional cryostats have long been the go-to tool for tissue sectioning, but they come with significant drawbacks—freezing damage, bulky design, and intensive maintenance. The Compresstome VF-510-0Z offers a modern alternative: a next-generation vibrating microtome that enables fast, reliable sectioning of live or fixed tissues—without the need […]
At Precisionary Instruments, we understand that preparing acute brain slices for electrophysiology is a highly technical and delicate process. Many researchers have reached out to us, looking for a clear and structured protocol that walks them through every step. In response, we have developed a detailed, step-by-step experimental guide, one of the first of its […]
Starting the year with fresh research goals? If improving your tissue sectioning workflow is a priority, our 30-day demo program for the Compresstome VF-510-0Z is the perfect opportunity to explore a vibratome that sections tissue faster, preserves sample integrity, and simplifies your lab work. We understand that some institutions require a demo before purchasing, and […]
Artificial Cerebrospinal Fluid (ACSF) is an essential buffer solution widely used in electrophysiology experiments, particularly to keep acute brain slices alive during research. This solution closely mimics the natural cerebrospinal fluid found in the brain and is designed to maintain neuronal viability and function during sensitive experiments like patch-clamp recordings. In this article, we will […]
In the realm of scientific research—particularly in histology, neuroscience, and pathology—the precise sectioning of biological samples is critical. Two primary instruments used for this purpose are vibratomes and microtomes. Each has its unique advantages and specific applications, as well as some overlapping uses. In this article, we will explore the different experimental applications for vibratomes […]
